Research Scientist (Applied LLMs), London

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   RESEARCH SCIENTIST (MACHINE LEARNING), LONDON YOUR IMPACT  As a Research Scientist in machine learning (ML), you will play an exciting role in building greenfield machine learning based models and algorithms that will power our platform to transform the drug discovery world as we know it.  Working in a highly creative, fast-paced and interdisciplinary environment, you will be partnering with leading engineers and scientists to conceive, design, and develop cutting edge machine learning algorithms to unlock new modelling and predictive power which will be critical to the organisation’s success. You will draw upon your existing deep research experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered computational biology and chemistry problems. Depending on your experience: You will create and lead projects, bringing together a variety of disciplined scientists and engineers to pursue some of the most ambitious modelling problems with deep learning - as well as providing technical mentorship and people management for others in the ML community at Isomorphic Labs You will be instrumental in leading greenfield machine learning based research projects, building the models, and algorithms that will power our platform to transform the drug discovery world as we know it. WHAT YOU WILL DO * Contribute to our research directions in machine learning by using your extensive knowledge of the field to apply world-leading ML algorithms to drug discovery. * Identify and create novel ML techniques and the required data to train. * Develop the architectures and training algorithms of machine learning models. * Analyse and tune experimental results to inform future experimental directions. * Implement and scale training and inference engineering frameworks. * Report and present research findings and developments clearly and efficiently, to both other ML scientists and scientists of different disciplines. * Iterate collaboratively with scientists and domain experts, sharing your own domain experience. * Suggest and engage in team collaborations to meet ambitious research goals. Depending on your experience: * Provide technical mentorship and guidance to the ML research community, advising on projects, and shaping our research roadmap based on your deep technical expertise. * Provide developmental support to other ML research scientists. * Create, lead, and run ML research projects, fostering collaborative and diverse teams to solve high priority modelling problems.Cultivate a diverse and inclusive research culture. SKILLS AND QUALIFICATIONS  Essential * PhD or equivalent practical experience in a technical field. * A proven track record in machine learning using deep learning techniques, including designing new architectures, hands-on experimentation, analysis, and visualisation. * Strong knowledge of linear algebra, calculus and statistics. * Experience using ML frameworks such as JAX, PyTorch, or TensorFlow, and scientific software such as NumPy, SciPy, or Pandas. * A passion for applying ML research to real world problems. * Depending on your experience: project supervision, leadership, or management. Nice to have * PhD in machine learning or computer science. * Relevant research experience to the position such as post doctoral roles, a proven track record of publications, or contributions to machine learning codebases. * Experience working in a scientific environment across disciplines (particularly biology, chemistry, physics). * Experience working with biological or chemical data and biological or chemistry software. * Experience working with real-world datasets. * Experience with ML on accelerators. * Experience in any of: large scale deep learning, generative models, graph neural networks, deep learning for drug discovery, deep learning for computer vision, 3D graphics/robotics, real-world applied RL. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   RESEARCH ENGINEERING (MACHINE LEARNING), LONDON  We are looking for Research Engineers with different levels of experience - Mid through to Senior, Staff, Principal or equivalent levels. YOUR IMPACT  This is an exciting opportunity for you to contribute to frontier research at the intersection of AI and drug design. Working in a highly creative, iterative environment, you will be partnering with scientists and engineers to advance foundational models that will transform the biopharmaceutical world as we know it.   You will draw upon your existing engineering and Machine Learning experience whilst learning from those around you, to apply novel techniques and ideas to newly encountered computational biology and chemistry problems. WHAT YOU WILL DO  Implementation & Optimisation: * Translate research concepts into practical implementations by developing and optimising state-of-the-art AI models, and building and maintaining robust codebases, data pipelines, and infrastructure for training and evaluation. Experimentation & Evaluation: * Design, implement, and run experiments to evaluate the performance and robustness of ML models, using a full spectrum of state-of-the-art machine learning methods. Evaluating, tuning, and maintaining AI/ML models (which includes collecting and preparing data as needed) Evaluation & Inference: * Implement algorithms and software to analyse and evaluate the performance of AI models. * Optimising performance of AI/ML models such as Diffusion models, Transformers, GNNs, leveraging a deep understanding of the AI/ML hardware+software stack * Advise on how to bring AI/ML models to production and/or integrating them into product offerings, and monitoring and refining their behavior. * Developing specialised tools/frameworks/infrastructure to aid in the work above Collaboration & Knowledge Sharing: * Work closely with research scientists and engineers, contributing to team discussions, sharing knowledge, and actively participating in code reviews to foster a collaborative environment. Innovation & Impact: * Proactively identify and address technical challenges, stay updated on the latest AI advancements, and focus on developing solutions that enable scaling our wider foundation and applied model platforms. * Ability to execute on independent engineering projects and software development towards research goals. SKILLS AND QUALIFICATIONS ESSENTIAL * Academic Background: Advanced degree (Master’s or PhD) in a highly quantitative field (Computer Science, AI, Physics, Mathematics, etc.) or equivalent practical experience. * ML Fundamentals: Deep understanding of machine learning principles and techniques. * Framework Expertise: Strong proficiency in deep learning frameworks such as JAX or PyTorch. * Modern Architectures: Hands-on experience building and working with modern model architectures (e.g., Transformers, GNNs, Diffusion Models). * Full ML Lifecycle: Experience taking models from conception to production (scoping, data analysis, training, debugging, evaluation, benchmarking, and deployment). * Engineering Excellence: Excellent software development skills with strong algorithms and data structures fundamentals. * Collaboration & Communication: An excellent team player with strong written and verbal communication skills, able to collaborate seamlessly in a cross-disciplinary environment. * Agency: Self-directed with an ability to navigate ambiguity, propose and own complex projects, learn the necessary context, and readily adapt to new domains and developments. Nice to have * Proven Research Record: A history of scientific contributions (e.g., publications at NeurIPS, ICML, ICLR, CVPR) or significant contributions to state-of-the-art AI models. * Scale & Performance: Experience training models across distributed systems (multi-GPU/multi-node) and optimising training and inference performance (e.g., XLA, Triton, CUDA, Pallas). * Domain Knowledge: A strong interest in, or knowledge of, biochemistry, computational biology, or drug discovery fundamentals. * Industry Experience: Proven track record working in reputable tech companies or research labs. * Applied ML: Experience developing models developed for real-world applications. * Infrastructure: Solid technical infrastructure knowledge and experience with low-level engineering (e.g., GCP, Kubernetes, Docker) CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

Apollo Research

Application deadline: We are conducting interviews actively and aim to fill this role as soon as we find someone suitable.   ABOUT THE OPPORTUNITY   We want to develop a “Science of Scheming”. The goal is ambitious and we’re looking for Research Scientists and Research Engineers who are excited to build a new hard science from the ground up.   YOU WILL HAVE THE OPPORTUNITY TO   - Collaborate with leading AI developers. We partner with multiple labs, giving you access to a breadth of models that no single AI lab could offer. Through long-term research collaborations, your work directly impacts how the most capable AI systems are built and deployed. - Deeply study the RL dynamics that lead to the emergence of reward-seeking, evaluation awareness or misaligned preferences. Design and train model organisms, and scale your insights to frontier systems. - Work towards “Scaling laws of scheming”. Build the empirical foundations to predict how scheming risks evolve as models scale in capability. - Develop novel and ambitious evaluation techniques that have a chance of scaling to highly evaluation aware models. - Deep dive into AI cognition. Discover patterns in the reasoning processes of frontier AI systems that no one else has ever observed before.   Note:  We are not hiring for interpretability roles.   KEY REQUIREMENTS    A diverse range of skill sets will be required to drive our research agenda forward and we don’t expect any single candidate to fulfill all the characteristics below. That being said, a successful candidate likely displays excellence at one or several of the following:   - Fast-paced empirical research: You can design and execute experiments. You always strive to speed up iteration cycles and relentlessly drive progress towards the next empirical milestone. - Conceptual insights about scheming: You have deeply thought about the problem of AI scheming and are familiar with all the relevant literature. You are able to turn vague and undefined concepts into concrete and insightful experiment proposals. - Software engineering skills: Strong software engineering skills correlate highly with effective execution, even in an era of AI agents. Our entire stack uses Python. - Intense interest in AI progress: You always stay up to date on the latest model releases, and continuously tinker with new and creative AI workflows to speed up your work. You are fascinated by AI cognition and actively spend time trying to understand how they think. - Experience RL-training LLMs: You have hands-on experience in training LLMs via reinforcement learning. You have encountered and resolved countless painful issues from GPU failures to debugging learning instabilities. - Strong analytical skills: You bring rigorous quantitative chops from working on fields such as scaling laws in LLMs, statistical physics, dynamical systems, applied statistics etc. You're comfortable building mathematical models of empirical phenomena and know how to extract signal from noisy data.   We want to emphasize that people who feel they don’t fulfill all of these characteristics but think they would be a good fit for the position, nonetheless, are strongly encouraged to apply. We believe that excellent candidates can come from a variety of backgrounds and are excited to give you opportunities to shine. We don’t require a formal background or industry experience and welcome self-taught candidates.