Senior II Engineer

Relation Therapeutics

ABOUT RELATION Relation is a sector defining TechBio company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure. We are scaling rapidly and building a team of exceptional individuals to push the boundaries of drug discovery. You will work in highly interdisciplinary teams where biology, computation, and engineering come together to solve complex problems that have not been solved before. Our state-of-the-art wet and dry labs in the heart of London are designed to accelerate this integration and translate insight into impact. We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the basis of gender, sexual orientation, marital or civil partnership status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. By joining Relation, you will help define how medicines are discovered and deliver meaningful impact for patients. THE OPPORTUNITY Relation is offering an outstanding opportunity for a Senior Scientist II / Principal Scientist, In Vivo Biology & Translational Science to help drive our growing discovery portfolio. We are looking for an experienced in vivo biologist with a strong track record of independently leading outsourced work packages through CRO partnerships and translating data into actionable project decisions, initially in support of our osteoporosis programme with scope to contribute across indications as the portfolio grows. In this role, you will own the design, delivery, and interpretation of in vivo pharmacology work packages, partnering closely with CROs and cross-functional colleagues across medicinal chemistry, biologics, DMPK, and safety. You will work at the intersection of experimental science and data-driven discovery within a growing TechBio company. DAY TO DAY, YOU WILL * Lead in vivo pharmacology strategy for projects within Relation's discovery programmes, proposing and championing the right study designs to support go/no-go decisions and milestone planning across multiple concurrent projects * Drive the execution, monitoring, and interpretation of in vivo pharmacology studies across target engagement, PK/PD, and disease-relevant efficacy endpoints * Own end-to-end CRO relationships for externally commissioned in vivo work packages: from vendor selection and SOW set-up through in-life liaison, data review, troubleshooting, and reporting * Commission in vivo-relevant in vitro and ex vivo assays, such as target engagement, pharmacodynamic, and mechanistic readouts, that directly inform study decisions and data interpretation * Translate biology data into clear, actionable insights and recommendations, communicating findings effectively to project teams and senior stakeholders * Maintain rigorous documentation standards across outsourced study packages, including ELN, protocol authoring and review, and study reporting * Champion Relation's collaborative, ambitious and science-driven culture, sharing scientific expertise across the team and helping to build an outstanding drug discovery organisation PROFESSIONALLY, YOU WILL HAVE * A PhD in Biology, Pharmacology, Biochemistry, or a related scientific discipline or equivalent experience in industrial drug discovery * Deep expertise in mammalian in vivo study design across target engagement, PK/PD, and efficacy endpoints, with the scientific judgement to define the right experiments to drive project decisions, a sound knowledge of 3Rs principles, and a proven record of delivering through CRO partnerships to quality and timeline * Experience commissioning or interpreting in vitro and ex vivo assays in support of in vivo programmes, including target engagement, pharmacodynamic, and mechanistic readouts * Experience across multiple stages of drug discovery (target ID through candidate selection) and across more than one disease area or physiological system * Scientifically rigorous and analytically critical, with the ability to interrogate data, challenge assumptions, and deliver across a broad and fast-moving project portfolio * Exceptional communication and stakeholder management skills: able to distil complex biology into clear project-level insights and influence cross-functional decisions * A deep passion for disease biology and drug discovery, with intellectual curiosity, enthusiasm for tackling complex scientific problems, and a drive to integrate emerging technologies with experimental science * Bonus experience: experience working across different drug discovery modalities, including small molecules and/or biologics; experience in a TechBio or AI-driven discovery environment. PERSONALLY, YOU * Are comfortable working in a matrixed environment, balancing multiple stakeholders and contributing effectively across teams. * Take ownership of your work, proactively seek opportunities to contribute, and enable others to do their best work. * Communicate openly and directly, give and receive feedback constructively, and handle challenging conversations with respect. * Actively seek out diverse perspectives, build strong working relationships, and contribute to shared goals across teams. * Embrace challenges with openness and resilience, set high standards for yourself, and strive to deliver meaningful outcomes. Working style & Culture at Relation At Relation, we operate in a matrixed, interdisciplinary environment, where impact is driven through collaboration across scientific, technical, and operational domains. We collaborate, and you will partner with colleagues across multiple teams and projects, contributing your expertise while aligning to shared company priorities. We work together and win together! The patient is waiting! Recruitment Agencies Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs.

Abound

About Abound We’re redefining consumer lending in the UK, and beyond. Using advanced AI and Open Banking data, we make fair, affordable personal finance available to more people. While traditional lenders rely almost entirely on credit scores, we look at the full financial picture - how much you spend, and what you can afford to repay to build a deeper, more accurate understanding of each customer's unique financial situation. And we've shown it works at scale. We’ve issued over £1.3bn in loans directly to customers while delivering market-leading credit performance - for every 10 defaults the industry expects, we see only 3. We also reached profitability just 2.5 years after launch. Backed by £2bn+ of funding from top-tier investors including Citi, GSR Ventures, and Deutsche Bank, we’re recognised as one of Europe’s fastest-growing fintechs (Sifted, CNBC). Now, we’re expanding into new markets and product lines - and we’re looking for ambitious people who want to learn fast, take ownership, and grow with us. About the Role We’re looking for a Software Engineer II to help build the systems that automate how our Finance and Operations teams work. As Abound scales, the manual workflows that powered us through our first £1bn of lending are becoming reliable, observable, automated systems- covering reconciliations, reporting, payments operations, collections workflows, and the day-to-day tooling our internal teams rely on. This is a hands-on engineering role on a small, high-impact team. You’ll write production code every day, taking well-scoped pieces of work from design through testing and deployment, with senior and lead engineers supporting you on the larger or more ambiguous problems. Over time you’ll grow ownership of the components and services you work on, and take on more of the discovery and design yourself. You won’t just close tickets. You’ll get close enough to the Finance and Operations workflows to understand the problem you’re solving, ask good questions, and care about whether the system actually works for the people using it. We value engineers who take ownership, communicate clearly, and want to keep levelling up- this role has a clear path toward Senior Software Engineer. Our technology stack: Python (FastAPI, SQLAlchemy, OpenTelemetry, Procrastinate), PostgreSQL, Liquibase, Docker, AWS Who you are * Solid experience building production systems in Python - you’re comfortable with type hints, write tests as a matter of habit, and have some exposure to async code (or are keen to learn) * Able to take a well-defined problem and deliver it end-to-end with limited guidance, while knowing when to ask for help on the bigger pieces * Care about code quality, reliability, and maintainability, especially when building for internal users where accuracy and auditability matter * A growing product mindset- you want to understand the problem behind the ticket, and you’re comfortable asking why * Curiosity about how finance and operations functions actually run (reconciliations, ledgers, reporting, payment flows, ops workflows), or a track record of picking up unfamiliar domains quickly * Clear communicator who works well with engineers and, increasingly, directly with business stakeholders * Comfortable in a fast-paced environment where accuracy, reliability, and clear communication are essential * Keen to grow - you take feedback well and want to develop toward more ownership and technical depth Nice to have * Experience working with relational databases and writing SQL (PostgreSQL especially) * Exposure to cloud infrastructure (AWS, GCP, or Azure) * Prior experience automating finance, accounting, or operations workflows * Interest or experience in lending, payments, or financial services more broadly * Exposure to observability tooling and supporting systems in production What you’ll be doing * Build and ship Python services and features that automate finance and operations workflows- from data ingestion through to the reports, actions, and exceptions that land with business users * Take well-scoped pieces of work from implementation through testing, deployment, and monitoring, with support from senior engineers on larger designs * Participate actively in code review, write meaningful tests, and help uphold the team’s engineering standards * Work alongside senior engineers and, increasingly, directly with Finance and Operations stakeholders to understand requirements and turn them into reliable systems * Grow ownership of the components and services you work on, taking on more of the design and discovery over time * Help support business-critical systems in production, troubleshooting issues that affect Finance and Operations users (with support as you build up context) * Contribute to the team’s delivery process sprint planning, sizing, and retrospectives * Make pragmatic technical decisions that balance shipping today with maintainability tomorrow What we offer * Everyone owns a piece of the company- equity * Hybrid with 3 days a week in the office * 25 days’ holiday a year, plus 8 bank holidays * 2 paid volunteering days per year * One month paid sabbatical after 4 years * Employee loan * Free gym membership * Team wellness budget to be active together-set up a yoga class, a tennis lesson or go bouldering

Storio group

Make Your Mark as an Engineering Manager II (Domain Platform Engineering & AI) at Storio group About the role You will lead our Domain Platform Engineering and AI team in London. This team acts as the backbone for our data consumers across Marketing, Finance, Operations, and Product. Your mission is to rebuild an enterprise data platform that supports a decentralized data model. This work ensures our colleagues have the trustable data and models they need to make great decisions for our customers. You will manage a growing team of engineers across the UK and the Netherlands. As we move from simplifying legacy systems into a phase of consolidation and growth, your leadership will be vital. You will help us create hyper-personalised experiences and make joy unforgettable for millions of people.