Senior Software Infrastructure Engineer

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   Your Impact We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible. As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow.  What You Will Do * Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications. * Design strategy and build roadmaps for maturing the platform. * Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack. * Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R&D cycles. * Deliver high-quality and well-tested user-focused features. Skills and Qualifications Essential: * Proven experience in architecting and managing large-scale AI/ML workloads in a production environment. * Expertise in cloud compute design, specifically within Google Cloud Platform (GCP). * Orchestration: Significant experience deploying and managing complex workloads within Kubernetes (GKE). * Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute. * Strong programming skills and a "reliability-first" approach to software development. Nice to Have: * A career history that spans both ML Software Engineering and Infrastructure SRE roles. * Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment. * Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking. * Experience with Google TPU generations and specialized ML-driven R&D cycles. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

Graphcore

ABOUT THE JOB Help prove the ML software stack that future AI systems will depend on. Graphcore is expanding the software systems behind AI compute at datacenter scale. This role focuses on validating a complex machine learning stack before it reaches customers and hardware.You will build the test infrastructure, automation and tooling that engineers trust every day. Your work will help raise reliability, performance and maintainability across frameworks, simulators, emulators and future hardware. You will shape test architecture across large codebases, CI pipelines and representative ML workloads. You will use strong software engineering judgement to turn complex technical goals into scalable validation systems. This is a role for someone who enjoys depth, ownership and useful engineering. You will make quality easier, faster and more visible for teams building at the edge of AI compute. THE TEAM AND CULTURE The ML QA team sits where Graphcore’s software components come together. Engineers work across unit tests, integration tests, full model runs, subgraph validation and benchmarking. Work is organised through focused squads with clear ownership. People are expected to step up, speak openly and improve how the team builds, tests and learns. Decisions are grounded in evidence from code, data and system behaviour. The team works closely with software teams to identify gaps, improve tooling and move priorities forward quickly. WHAT WE’RE LOOKING FOR · Strong software design skills, with experience building maintainable systems across large codebases. · Production Python experience, including testable, reliable code used by other engineers. · Experience with CI/CD, automated testing and Linux based development workflows. · Familiarity with C or C++, with confidence reading and debugging low level code. · Understanding of ML frameworks, workloads or model execution beyond simple API usage. · Ability to mentor engineers, improve practices and take ownership of complex technical problems. BENEFITS · Unlimited annual leave · Up to 5% matched pension · Phantom equity – share in Graphcore’s success · True flexibility in how and where you work · Office spaces designed for collaboration · Free food and an on-site barista · Health cash plan · Income protection · Life assurance · Along with other benefits you can choose from (private medical insurance, dental plan etc) We welcome people from all backgrounds and experiences and are committed to building an inclusive environment where everyone can do their best work. We’re an equal opportunity employer and recognise that everyone brings different strengths and perspectives. If you need any adjustments during the interview process, just let us know - we’re happy to support you. JOIN THE TEAM AT GRAPHCORE Graphcore is one of the world’s leading innovators in Artificial Intelligence compute. It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone. Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore brings together deep expertise to solve complex problems and deliver meaningful progress in AI compute. If you want to shape how complex ML software is tested, trusted and improved, we’d love to hear from you. Apply now to be part of the journey.

On

IN SHORT  As a Senior Engineer in the Digital Twin team, you will develop the technological infrastructure that enables On to identify products across warehouses, retail stores and beyond using technologies such as RFID. As part of the Operations cluster, this team plays a key role in how we integrate with our supply chain, warehouse and commercial partners, influencing the future success of On. At On, we believe everyone in the world should have access to the best sportswear. For this to happen, we need high performing solutions to ensure that the right product gets to the right customer at the right time, while making the overall process efficient, environmentally friendly and sustainable. YOUR MISSION  * Write well-tested, scalable and reliable code that integrates On’s ERP system with RFID solutions * Develop, maintain and operate cloud-native applications using microservice architectures * Work with your team to design, evaluate and plan forward-looking projects that take On to the next level of technology * Drive technical projects that help us create more robust services * Help shape On’s engineering culture and contribute to its current and future success YOUR STORY  * Extensive experience with TypeScript tech stacks on the backend * Proficient in leading the development of large scale systems in your team * Proven track record of developing, deploying and maintaining cloud-native applications * Build strong collaborative relationships with other engineers, product and business stakeholders * Strong ability to work with a wide range of teams and stakeholders * Past technical experience with ERP and RFID systems and logistics processes or an interest in diving into this area * You communicate effectively in both remote and on-site working environments * Bonus: experience with our current tech stack (Kubernetes, Kafka, MS Dynamics F&O, Terraform) MEET THE TEAM  At On, we believe everyone in the world should have access to the best sportswear. For this to happen, we need high performing solutions to ensure that the right product gets to the right customer at the right time, while making the overall process efficient, environmentally friendly and sustainable. WHAT WE OFFER  On is a place that is centered around growth and progress. We offer an environment designed to give people the tools to develop holistically – to stay active, to learn, explore and innovate. Our distinctive approach combines a supportive, team-oriented atmosphere, with access to personal self-care for both physical and mental well-being, so each person is led by purpose. On is an Equal Opportunity Employer. We are committed to creating a work environment that is fair and inclusive, where all decisions related to recruitment, advancement, and retention are free of discrimination.