Principal Engineer - Edge Delivery & Observability

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   Your Impact We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible. As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow.  What You Will Do * Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications. * Design strategy and build roadmaps for maturing the platform. * Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack. * Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R&D cycles. * Deliver high-quality and well-tested user-focused features. Skills and Qualifications Essential: * Proven experience in architecting and managing large-scale AI/ML workloads in a production environment. * Expertise in cloud compute design, specifically within Google Cloud Platform (GCP). * Orchestration: Significant experience deploying and managing complex workloads within Kubernetes (GKE). * Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute. * Strong programming skills and a "reliability-first" approach to software development. Nice to Have: * A career history that spans both ML Software Engineering and Infrastructure SRE roles. * Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment. * Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking. * Experience with Google TPU generations and specialized ML-driven R&D cycles. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

Toast

This hybrid role is based in Dublin, Ireland (Full relocation provided). Toast creates technology to help restaurants and local businesses succeed in a digital world, helping business owners operate, increase sales, engage customers, and keep employees happy. Your mission is to drive architecture, technical strategy, and implementation of AI agents for Toast's Team area which is part of the Fintech line of business. You will be one of the most senior technologists in line of business. The Team area is a mission-critical space on which our restaurants rely to manage their staff and optimize their labor. Beyond being on the forefront of agent development, your scope will also include enablement and leadership for how software is developed at Toast through adoption of bleeding edge spec driven development and other paradigms.  A day in the life (Responsibilities) * Develop and drive an architectural vision to support the ambitious goals for agents and agent development * Be an active participant and an authoritative technical voice in FinTech product strategy discussions * Partner with the Team Management Director of Engineering and Sr. Director of Product to successfully deliver Team agent products from design to production * Work closely with other Senior Principal Engineers to further the agent patterns and ecosystem across Toast as a whole * Evolve an ever more efficient way of working through agents and spread it across Toast * Work directly with the product manager for the Team Agent space, collaborating to drive vision * Be hands on and actively participate in development on the Team Agent * Mentor and develop technical leadership across Team, and Fintech What you'll need to thrive (Requirements) * 15+ years experience designing and building highly scalable, mission-critical distributed and fullstack software systems * 10+ years experience building and operating SaaS products, ideally AWS hosted * 1+ years experience using the latest in coding agents  * A strong desire to lean all in on agentic development practices * Passion for building autonomous agents * Demonstrated ability to drive technical architecture for a company or highly scalable line of products * A desire to work not only with technologists but also product owners and business leaders * Ability and desire to draw big lines and boxes on a whiteboard paired with the ability to dig in and understand the ebb and flow of what the code is doing under load * Ability and desire to communicate and influence at the executive level What will help you stand out (Nonessential Skills/Nice to Haves) * Experience designing agentic products * Experience building systems that leverage LLMs and other ML models * Experience with enterprise integration using Apache Camel * Experience architecting event-driven distributed systems using Apache Pulsar * Experience defining test, build and deploy strategies * Solid understanding of workforce management * Solid understanding of restaurant operations #LI-HYBRID #BI-Hybrid   AI at Toast At Toast, one of our company values is that we're hungry to build and learn. We believe learning new AI tools empowers us to build for our customers faster, more independently, and with higher quality. We provide these tools across all disciplines, from Engineering and Product to Sales and Support, and are inspired by how our Toasters are already driving real value with them. The people who thrive here are those who embrace changes that let us build more for our customers; it’s a core part of our culture. Our Total Rewards Philosophy  We strive to provide competitive compensation and benefits programs that help to attract, retain, and motivate the best and brightest people in our industry. Our total rewards package goes beyond great earnings potential and provides the means to a healthy lifestyle with the flexibility to meet Toasters’ changing needs. Learn more about our benefits at https://careers.toasttab.com/toast-benefits. How Toast Uses AI in its Hiring Process Throughout the hiring process, our goal is to get to know you. We use AI tools to support our recruiters and interviewers with tasks like note-taking, summarization, and documentation of interviews to ensure they can be fully focused on your conversation. All hiring decisions are made by people. To learn more: https://careers.toasttab.com/ai-in-hiring Our Approach to Hybrid Working We embrace a hybrid work model that fosters in-person collaboration while valuing individual needs. Our goal is to build a strong culture of connection as we work together to empower the hospitality community, regardless of location. Please visit the Locations page on our career site to learn more about our in-office expectations by region: https://careers.toasttab.com/locations-toast Diversity, Equity, and Inclusion is Baked into our Recipe for Success At Toast, our employees are our secret ingredient—when they thrive, we thrive. The restaurant industry is one of the most diverse, and we embrace that diversity with authenticity, inclusivity, respect, and humility. By embedding these principles into our culture and design, we create equitable opportunities for all and raise the bar in delivering exceptional experiences. We Thrive Together We embrace a hybrid work model that fosters in-person collaboration while valuing individual needs. Our goal is to build a strong culture of connection as we work together to empower the restaurant community. To learn more about how we work globally and regionally, check out: https://careers.toasttab.com/locations-toast. Apply today! Toast is committed to creating an accessible and inclusive hiring process. As part of this commitment, we strive to provide reasonable accommodations for persons with disabilities to enable them to access the hiring process. If you need an accommodation to access the job application or interview process, please contact candidateaccommodations@toasttab.com. ------ For roles in the United States, it is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Tripadvisor

About Tripadvisor  The Tripadvisor Group connects people to experiences worth sharing, and aims to be the world’s most trusted source for travel and experiences. We leverage our brands, technology, and capabilities to connect our global audience with partners through rich content, travel guidance, and two-sided marketplaces for experiences, accommodations, restaurants, and other travel categories. The subsidiaries of Tripadvisor, Inc. (Nasdaq: TRIP), include a portfolio of travel brands and businesses, including Tripadvisor, Viator, and TheFork. The Tripadvisor Experiences Engineering team is distributed across Europe and is responsible for the platform, mobile apps and all their supporting infrastructure. We run the systems that help operators build their businesses and those which enable third parties to utilise our inventory. We provide the tools which help our customer services team provide world class service to travellers and operators internationally. About the role We're looking for a Principal Product Engineer who pairs deep engineering craft with strong product instincts. You'll work across the stack - mobile, web, backend - wherever the highest-leverage problem happens to live that quarter. You don't wait for a perfectly scoped ticket; you partner with product, design, and data to figure out what's worth building, then ship it end-to-end. We expect breadth. We also expect real depth in the mobile app ecosystem - our customer-facing experiences live there. But we're not hiring a mobile only specialist. We're hiring a generalist with mobile chops who can lead an iOS architecture review on Tuesday and untangle a backend latency regression on Wednesday.   What you'll do * Identify, scope, and ship the changes that move business metrics - across mobile, web, services, and data layers * Architect long-lasting systems that hold up under real production conditions: performance, reliability, scalability, offline behavior, consistency * Lead technical design reviews across teams, weighing trade-offs not just in code but in product impact, time-to-ship, and operational cost * Drive operational maturity wherever it's weakest - release management, observability, incident response, performance monitoring - including in the mobile apps * Partner with PMs, designers, and engineering leaders to shape what we build, why, and in what order; you're a peer in those conversations, not a downstream implementer * Set the technical bar for the org by example: write the prototype, prove the pattern, then teach it * Communicate trade-offs clearly to engineers, product partners, and senior stakeholders   What we're looking for * 10+ years of software experience, with significant time still spent hands-on in code - track record of shipping product-impacting work end-to-end, not just owning a layer * Real depth in the mobile app ecosystem (iOS and/or Android, with strong fluency in Swift and/or Kotlin and the surrounding ecosystem - offline sync, push, auth, persistence, networking, REST/GraphQL) - and credible breadth beyond it * Demonstrated breadth: you've worked seriously in at least one of {web frontend, backend services, data/infra, platform tooling} alongside mobile, and can hold your own in code review there * Strong product judgment: you've made calls about what not to build, and can defend them with evidence * Comfort troubleshooting in production across stacks - crash analysis, latency tracing, release-health debugging * Excellent cross-functional collaboration; you make the people around you better   Nice to have * Background in marketplaces, bookings, or other transactional consumer products * Time spent close to data - experimentation, analytics instrumentation, or ML-adjacent work   Our Cultural Pillars: Traveler first We exist to create value for our customer, the traveler. We enable our suppliers and partners to unlock this value. Their collective behaviors and insights are what drives us.  Execution is our edge We act fast, experiment, learn from failure, iterate, and improve the solutions of tomorrow across every aspect of our business. Our execution is agile, data-driven, prioritised, and built to scale. We assume no problem is someone else’s problem and finish what can be done today, knowing tomorrow will bring fresh challenges.  We succeed together The best outcomes are driven by empathic, humble, and diverse subject matter experts working toward shared goals. We collaborate relentlessly, challenge assumptions, give actionable feedback, and set each other up for success through empowered teams with a clear charter. We transparently take ownership of our growth, individually and as a team. We celebrate the quality of our effort, our learnings, and our collective achievements.     We strive to create an accessible and inclusive experience for all candidates. If you need a reasonable accommodation during the application or the recruiting process, please make sure to reach out to your individual recruiter or our team at AccessibleRecruiting@tripadvisor.com. If you have any additional questions about careers at Tripadvisor you can email us at recruitment@tripadvisor.com. We have all the answers!   #LI-SM1 #LI-Remote #LI-Hybrid