Scientist, Antibody Developability

Adaptyv Bio

Adaptyv is building an automated lab that lets AI agents run biology experiments. We're entering the era of agentic science where AI models can now design novel proteins, propose hypotheses, and iterate on experimental results. But they can't run the experiments themselves - that's still a manual, months-long process. We're building the infrastructure that gives AI agents access to the physical world. We are one of the fastest growing biotech companies, trusted by leading biopharmas, frontier AI labs, and the techbio companies pushing the field forward. This is a rare chance to help advance some of the most important work happening in biotech today. Our automated lab is powered by a deep software + hardware stack: lab instruments worth millions of USD reverse-engineered into API-controllable hardware, dozens of devices orchestrated through complex workflows, full observability on everything that happens in the lab, processing pipelines for messy physical-world data, and AI systems that troubleshoot production results and accelerate assay development. We’re growing rapidly and are hiring for talented people to scale and support the massive demand for AI-driven wet lab experimentation. ABOUT THE ROLE You'll build out analytical characterization at Adaptyv — the forensic layer that tells a customer the truth about their molecule: its identity, purity, integrity, aggregation state, and modifications. HPLC and mass spectrometry are the core of this, applied across the full antibody stack and beyond. This is a build role, not a service-desk role. Today these methods are bespoke; your job is to turn them into automated, high-throughput, productized characterization that any customer can order and trust. You'll develop the methods hands-on, then work across teams to make them a reliable part of the platform — with the biology team to fit them into workflows, with lab automation to scale and automate them, and with software to capture, process, and interpret the data. You'll lead the science without retreating into management. WHAT YOU'LL DO * Develop, validate, and run analytical methods hands-on: HPLC (SEC, IEX/CEX, RP, HILIC) and LC-MS — intact and subunit mass, peptide mapping, PTM and glycan analysis, purity and identity. * Build the analytical characterization menu for the full antibody stack (and other biologics) into a productized, orderable capability. * Partner with lab automation to bring methods onto automated, high-throughput systems with reproducible turnaround. * Work with the software team to structure the data, build analysis and QC pipelines, and turn spectra and chromatograms into clean, interpretable results. * Set the quality bar: troubleshoot instruments and methods, define acceptance criteria, and own the integrity of what we report. * Advise customers and internal teams on what the data actually means. WHAT WE'RE LOOKING FOR * Deep, hands-on expertise in HPLC and mass spectrometry for proteins/biologics — method development and validation, not just running fixed SOPs. * Applied industry experience. You've delivered analytical characterization in a production, manufacturing, QC, or commercial CRO setting — where results had to be right, fast, and reproducible at volume. This is the core requirement: we're not looking for a primarily academic profile who did this in a single research project. * Strong on the antibody / biologics analytical stack — you know what "good" looks like for identity, purity, aggregation, and PTMs. * Builder who moves fast. You like setting up new capabilities and getting them running, not maintaining the status quo. * Interdisciplinary. You're comfortable working shoulder-to-shoulder with automation engineers and software people, and you see data and automation as part of your job, not someone else's. * Comfort turning method data into pipelines (some scripting / data fluency) is a strong plus. DETAILS * Location: Lausanne, Switzerland (on-site) * Type: Full time * Start date: ASAP Application deadline We are reviewing applicants on a rolling basis.

Adaptyv Bio

Adaptyv is building an automated lab that lets AI agents run biology experiments. We're entering the era of agentic science where AI models can now design novel proteins, propose hypotheses, and iterate on experimental results. But they can't run the experiments themselves - that's still a manual, months-long process. We're building the infrastructure that gives AI agents access to the physical world. We are one of the fastest growing biotech companies, trusted by leading biopharmas, frontier AI labs, and the techbio companies pushing the field forward. This is a rare chance to help advance some of the most important work happening in biotech today. Our automated lab is powered by a deep software + hardware stack: lab instruments worth millions of USD reverse-engineered into API-controllable hardware, dozens of devices orchestrated through complex workflows, full observability on everything that happens in the lab, processing pipelines for messy physical-world data, and AI systems that troubleshoot production results and accelerate assay development. We’re growing rapidly and are hiring for talented people to scale and support the massive demand for AI-driven wet lab experimentation. ABOUT THE ROLE You'll build out cell-based and functional assays at Adaptyv — the work that proves an antibody or protein actually does something: activates or blocks a receptor, triggers signaling, kills a cell, or modulates an immune response. Cell activation assays, reporter systems, potency assays, and antibody functional readouts are the heart of this role. This is the most interdisciplinary of our scientist roles. A new functional assay starts as bespoke science and has to become a reliable, automated product. You'll design and run the assays hands-on with the biology team, work with lab automation to make them robust and high-throughput, and work with the software team to capture, model, and interpret the data — turning messy cell-based readouts into clean, comparable results. You'll guide and lead, but the value is in setting up real, working assays, not in managing. WHAT YOU'LL DO * Develop, qualify, and run cell-based functional assays hands-on: cell activation and signaling, reporter-gene assays, potency assays, and antibody functional readouts (e.g. agonism/antagonism, ADCC/CDC-type functional effects, T-cell activation, cytokine readouts). * Turn bespoke functional assays into productized, orderable capabilities with defined, reproducible performance. * Work with the biology team to integrate assays into production workflows, and with lab automation to scale them onto automated systems. * Partner with the software team to structure and model functional data — dose-response, potency, normalization — and make it interpretable and comparable across runs. * Own assay robustness: controls, reference standards, troubleshooting, and the quality bar for what we report. * Advise customers and internal teams on assay design and what the functional data means. WHAT WE'RE LOOKING FOR * Deep, hands-on experience developing cell-based and functional/potency assays — reporter cell lines, primary cells, flow cytometry, and the realities of making cell assays reproducible. * Applied industry experience. You've built and run these assays in a production, development, or commercial setting where throughput and reliability mattered — not primarily in an academic research project. This is the core requirement. * Strong on antibody / protein function — you understand mechanism well enough to design the right assay for the question. * Builder who moves fast. You like standing up new assay capabilities and productizing them. * Genuinely interdisciplinary. You're energized by working across biology, automation, and software, and you treat data modeling and automation as part of the assay, not an afterthought. * Data fluency (scripting, analyzing dose-response and potency data) is a strong plus. DETAILS * Location: Lausanne, Switzerland (on-site) * Type: Full time * Start date: ASAP Application deadline We are reviewing applicants on a rolling basis.

Adaptyv Bio

Adaptyv is building an automated lab that lets AI agents run biology experiments. We're entering the era of agentic science where AI models can now design novel proteins, propose hypotheses, and iterate on experimental results. But they can't run the experiments themselves - that's still a manual, months-long process. We're building the infrastructure that gives AI agents access to the physical world. We are one of the fastest growing biotech companies, trusted by leading biopharmas, frontier AI labs, and the techbio companies pushing the field forward. This is a rare chance to help advance some of the most important work happening in biotech today. Our automated lab is powered by a deep software + hardware stack: lab instruments worth millions of USD reverse-engineered into API-controllable hardware, dozens of devices orchestrated through complex workflows, full observability on everything that happens in the lab, processing pipelines for messy physical-world data, and AI systems that troubleshoot production results and accelerate assay development. We’re growing rapidly and are hiring for talented people to scale and support the massive demand for AI-driven wet lab experimentation. ABOUT THE ROLE You'll build out protein expression and purification at Adaptyv, with a focus on mammalian systems — CHO and HEK, transient and stable. This is the foundation the rest of the platform stands on: titers, quality, and turnaround here set the ceiling for everything downstream. Your job is to take expression and purification from bespoke, person-dependent protocols to a robust, automated, high-throughput product. You'll optimize and run the science hands-on, work with lab automation to scale it onto liquid handlers and automated systems, and work with the software team to track samples, capture process data, and make production observable and predictable. You'll lead the science and stay deeply hands-on. WHAT YOU'LL DO * Develop, optimize, and run mammalian expression hands-on (CHO/HEK, transient and stable), pushing titer, quality, and reproducibility. * Own purification across modalities (Protein A, IEX, SEC, and related) and the quality of the proteins we ship. * Turn expression and purification into a productized, high-throughput, automated capability with predictable turnaround. * Partner with lab automation to scale workflows onto automated systems, and reduce manual, person-dependent steps. * Work with the software team to track samples and process parameters, and make production yields and quality observable and improvable. * Set the quality bar and troubleshoot the inevitable failures across biology, reagents, and process. WHAT WE'RE LOOKING FOR * Deep, hands-on expertise in mammalian protein expression and purification — CHO/HEK, and the full path from construct to purified, characterized protein. * Applied industry experience. You've run expression and purification in a production or industrial setting — where yield, reproducibility, and turnaround mattered at scale — not primarily in an academic research project. This is the core requirement. * Track record of making production reliable — titer optimization, scale-up, and consistent quality, not one-off preps. * Builder who moves fast. You want to stand up and continuously improve a production capability, not run a fixed protocol. * Interdisciplinary. You collaborate naturally with automation engineers and software people, and you see automation and data as core to a modern production process. * Data fluency (scripting, tracking and analyzing process data) is a strong plus. DETAILS * Location: Lausanne, Switzerland (on-site) * Type: Full time * Start date: ASAP Application deadline We are reviewing applicants on a rolling basis.