Scientist, Macrophage & Myeloid Biology

Engitix

YOUR MISSION We are seeking an accomplished Senior scientist of macrophage biology to provide scientific leadership in macrophage biology and immune-stromal interactions, driving target identification, validation and translational strategy across our fibrosis and oncology discovery portfolio.  We are looking for an expert in macrophage biology who will use their experience to establish macrophage-based target screening assays combined with our novel extracellular matrix-based cell models, utilising cellular, immunological, biochemical, molecular biology and functional genomic approaches. You will also provide scientific mentorship and technical guidance to scientists across discovery programmes, champion innovative approaches and emerging technologies in macrophage and immune-stromal biology, and represent macrophage biology expertise within cross-functional project teams. Key Responsibilities * Establish a suite of macrophage functionality assays to target discovery and drug discovery flowcharts, including activation, cytokine secretion, phagocytosis and efferocytosis assays. * Optimise macrophage target screening-based systems utilising annotated lmw libraries and functional genomic approaches such as siRNA and CrispR library-based approaches. * Lead a small team of immunologists/cell biologists involved in execution of projects across both the internal and external biopartnerships. * Lead the build novel macrophage drug target nomination packages and present case to the leadership for portfolio entry. * Analyse, interpret, report and present results. YOUR PROFILE Key Experience * Demonstrable expertise in macrophage biology, in particular phagocytosis pathways. * Demonstrable experience in target nomination and validation in a biotech or pharmaceutical based setting. * Expertise in the use of multi-colour flow cytometry and IF techniques. * Hands-on experience of key immunological and molecular biology techniques including MSD, RNA/DNA. extraction, qRT-PCR, western blotting, siRNA knockdown. * Have team and direct people leadership experience. * Familiarity with molecular pharmacology and oncology drug development would be an advantage. * Prior working experience in the biotech/pharma industry performing laboratory research would be a further plus.   Qualifications and Competencies * PhD in Biomedical sciences, Immunology, Biochemistry, Biotechnology or related discipline plus 4 years’ experience in drug screening setting or MSc plus 8 years practical experience  with a focus on immuno-oncology or fibrosis. * Ability to plan, execute and critically assess experiments independently. * Excellent time-management skills and ability to work to set deadlines. * You will be expected to work well within a team, have strong written and verbal communication skills, as well as IT skills. * You will troubleshoot effectively, work methodically, stay well organised, pay close attention to detail, and maintain accurate records. WHY US? * Be part of a pioneering biotech transforming drug discovery through ECM biology * Work in a collaborative, fast-paced environment with opportunities to shape the future of targeted therapeutics * We offer a competitive package including private medical insurance, pension, bonus, employee perks and more!

Sway Sourcing Sweden AB

Om uppdraget 🔬 Du kommer att ingå i ett Bioscience Immunology-team inom Research and Early Development, Respiratory & Immunology. Rollen fokuserar på in vitro-studier och ex vivo-analyser av musceller med inriktning mot inflammatoriska och autoimmuna sjukdomar. Området Respiratory & Immunology är ett av organisationens kärnterapiområden och har som mål att förstå, behandla, modifiera och i förlängningen bota respiratoriska och autoimmuna sjukdomar. Uppdraget passar dig som vill arbeta nära forskningen, bidra till läkemedelsutveckling och vara delaktig i att generera robusta, publicerbara vetenskapliga resultat. Dina arbetsuppgifter 🔍 I rollen planerar, genomför och analyserar du in vitro- och ex vivo-experiment som stödjer läkemedelsutvecklingsprojekt. Du bidrar aktivt i vetenskapliga diskussioner kring studiedesign och tolkning av data samt presenterar resultat, slutsatser och rekommendationer i projekt- och teamforum. Arbetet är praktiskt och hands-on, där du utför analyser kopplade till prekliniska studier i nära samarbete med andra forskare. Du ansvarar för att säkerställa högsta kvalitet vad gäller dataintegritet, kvalitetssäkring och arkivering samt för att sammanställa rapporter och vetenskapliga sammanfattningar. Din profil / Obligatoriska kompetenser ✅ Masterexamen i biologi eller närliggande område Minst 5 års erfarenhet av flödescytometri (FACS) på musmaterial, inklusive organpreparering, digestion, färgning och antikroppspaneldesign God vana av BD FACSDiva-instrument och analys i FlowJo Förmåga att självständigt planera, genomföra och analysera proteinanalyser såsom ELISA, Western blot och Meso Scale Discovery Erfarenhet av RNA-arbete inklusive extraktion och qRT-PCR Förståelse för statistik, datakvalitet, rapportering och arkivering Mycket god engelska i tal och skrift samt stark presentationsförmåga Meriterande färdigheter ⭐ Doktorsexamen inom immunologi Djup förståelse för autoimmuna sjukdomar, särskilt inom mag-, hud- eller ledimmunologi Erfarenhet av in vivo-modeller för inflammation och autoimmunitet Erfarenhet av cellisolering och cellsortering, exempelvis MACS, StemCell Technologies och FACS-baserad sortering Erfarenhet av cellodling och in vitro-assays med murina leukocyter Personliga egenskaper 🤝 Du är analytisk, noggrann och har ett starkt vetenskapligt driv. Du trivs med praktiskt laboratoriearbete men uppskattar också att diskutera data och slutsatser i grupp. Du arbetar strukturerat, tar stort ansvar för kvalitet och leverans och har lätt för att kommunicera komplexa resultat på ett tydligt sätt. Språk 🌍 Mycket god engelska i tal och skrift. Plats: Göteborg Omfattning: Heltid, 100 % Period: 2026-03-16 – 2026-12-31 Sista ansökningsdag: 15 mars 2026 Sway Sourcing är en innovativ rekryteringspartner som specialiserar sig på att matcha rätt talang med rätt företag – snabbt och effektivt. Vårt huvudfokus ligger inom Ekonomi, Administration, HR, Marknad och IT, men vi har även den breda expertis och flexibilitet som krävs för att leverera skräddarsydda rekryteringslösningar inom alla branscher. Trots att vi är en relativt ny aktör har vi redan byggt förtroende hos många av Sveriges största företag och arbetar både nationellt och internationellt. Med baser i Sverige och Spanien erbjuder vi en unik kombination av lokal expertis och global räckvidd. Vårt starka nätverk och djupa branschinsikter gör oss till en självklar partner för företag som vill ligga steget före i sin rekrytering.

Professional Galaxy AB

Professional Galaxy is an IT and technology consulting company that provides highly specialized expertise within IT, software development, SAP, purchasing, electronics and mechanical design. We collaborate with experienced senior experts and deliver strategic value-creating expertise to some of Sweden's most complex and analytically demanding projects. Our focus is always on high quality, professionalism and clear, measurable results. Are you the right person for the assignment, or do you want to recommend a strong candidate? Do not hesitate to contact us. Apply today, selection and interviews are ongoing. Job summary We are looking for a Scientist In Vivo & In Vitro respiratory for our client. About the role: Join the Bioscience Asthma & Skin Immunity in vivo team within Research and Early Development, Respiratory & Immunology. You will support in vitro and in vivo studies, and ex vivo analyses. Respiratory & Immunology is one of AstraZeneca’s core therapy areas, aiming to understand, treat, modify, and ultimately cure respiratory and autoimmune diseases. What you will do: • Plan and execute experiments: Design, perform, and analyze in vitro and ex vivo studies to advance drug discovery projects and generate publishable insights. • Support in vivo experiments Accountabilities: • Hands on work: Conduct in vitro and ex vivo analysis from rodent studies alongside a team of committed scientists; support in vivo scientists with preparations for experiments, collecting biological samples and live animal handling. • Data responsibilities: Uphold the highest standards of data integrity, quality control, and archiving. • Communication: Evaluate and interpret primary data; write reports and summaries; present in team and project meetings. Essential for the role: • Cellular/molecular techniques: Ability to independently plan, execute, and analyze protein expression/activation assays (ELISA, Meso Scale Discovery) and RNA analysis (extraction, qRT PCR). • In vivo experience: Hands-on experience with rodents including live animal handling, drug administration through different routes, blood and organ sampling and processing. Valid education required for compliance to work with live animals in Sweden (LAS, FELASA) • Data and statistics: Understanding statistical methods, quality control, reporting, and data archiving. • M.Sc. degree in relevant subjects or equivalent level of understanding developed through experience in academia or drug discovery settings. Desirable for the role: • Experience in lung function measurements in rodents Soft skills: • Communication: Excellent written and spoken English • Strong presentation skills. Startdatum: 2026-04-20 Slutdatum: 2026-12-31 Application Deadline: 2026-03-30 Please apply directly through our system with: - Your updated CV in english - Availability to start the assignment In the motivation, describe why you are suitable for this assignment - refer to previous consulting assignments, employment, education and personal qualities. Please note: We do not accept any applications through mail. All applications have to be sent through the portal to be valid. Offer continuously: Please note that for this role we offer continuously. That means that we sometimes remove the assignments before the deadline. If you are interested, we recommend that you apply immediately.