
Isomorphic Labs · London
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve a...
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing
medicines with an ambition to solve all disease.
The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are
curtailed or cured starting with better and faster drug discovery.
Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards
us achieving our ambitious goals, while being a part of an inspiring and collaborative culture.
The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.
Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold
system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new
predictive and generative AI models that accelerate scientific discovery at digital speed.
Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s
powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs
will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases.
We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic
areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance
rational drug design.
Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious
mission to one day solve all disease with the help of AI.
We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a key role
and work at a grand scale to deliver the foundations that make this happen. By partnering with in-house machine learning experts
and biotech researchers you will join a team to efficiently scale and plan the base on which our groundbreaking AI is built.
integrating new hardware to leverage advancements. In partnership with our Machine Learning Platform team, regularly work in
the environment to push and support deployments. Regularly be building, monitoring and managing cluster deployments.
with hardware benchmarking
We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide
our work and will continue to strengthen it.
Thoughtful
Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science
every single day.
Brave
Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.
Determined
Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to
deliver on it. Because disease won’t wait, so neither should we.
Together
Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is
a group project, and remembering that what we’re doing will have a real impact on real people everywhere.
We believe that to be successful we need a team with a range of skills and talents. We're building an environment where
collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique
experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact.
We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin,
disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or
related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional
need that requires accommodation, please do not hesitate to let us know.
It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this
if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the
office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional
needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an
initial screening call.
Please note that when you submit an application, your data will be processed in line with our privacy policy.
>> Click to view other open roles at Isomorphic Labs
About Man Group Man Group is a global alternative investment management firm focused on pursuing outperformance for sophisticated clients via our Systematic, Discretionary and Solutions offerings. Powered by talent and advanced technology, our single and multi-manager investment strategies are underpinned by deep research and span public and private markets, across all major asset classes, with a significant focus on alternatives. Man Group takes a partnership approach to working with clients, establishing deep connections and creating tailored solutions to meet their investment goals and those of the millions of retirees and savers they represent. Headquartered in London, we manage $228.7 billion* and operate across multiple offices globally. Man Group plc is listed on the London Stock Exchange under the ticker EMG.LN and is a constituent of the FTSE 250 Index. Further information can be found at www.man.com At Man Group, we respect your privacy and we are committed to protecting and safeguarding your Personal Data. We have developed policies and processes which are designed to provide for the security and integrity of your Personal Data. We are committed to Processing your Personal Data fairly and lawfully, and being open and transparent about such Processing. For further information on how we process your data, please see the privacy notice for applicants here * As at 31 March 2026 The Role At Man Group, we run large Python research compute clusters. We have a long history of pioneering technology in finance, and this role presents the opportunity to join us, as we work towards building scalable compute for research and software development to help identify and execute on investment opportunities. We are looking for a high-performing Senior Python Platform Engineer to build solutions that make use of the latest capabilities in compute infrastructure. This role is at the intersection of technology and finance, helping to deliver high-impact, novel solutions that touch every part of our business. Working in our Developer Platform team, you will build the core research platform and infrastructure used across Man Group. You will also partner with teams across the business to create APIs and frameworks that allow researchers and developers to augment, automate and transform our investment and operational workflows. Role Responsibilities * Lead the design, build and maintenance of Man’s core Python compute platform * Partner with stakeholders in research, trading and technology, to design and build open-source cluster-compute technologies * Be aware of and actively monitor the latest developments in applied cluster compute, particularly Python facing libraries and tools * Identify and implement novel solutions - we take the best of what the open-source world has to offer and make it fit our needs, often contributing back to upstream projects * Proactively engage with teams across the business to promote understanding and adoption of our compute cluster capabilities Key Competencies Essential * Advanced proficiency in Python, with extensive professional experience in building production applications and services * Experience of modern cluster compute - Kubernetes, Spark, Hadoop Yarn, Ray, Airflow are some of the technologies we use * Experience leading work in a formal software development environment alongside other engineers in a collaborative manner * Strong experience building platforms on the Linux Operating System * Self-organised with the ability to effectively manage time across multiple projects with competing business demands and priorities * Strong interpersonal skills with the ability to establish and maintain a close working relationship with quantitative developers, researchers, and other stakeholders Advantageous * Academic record including a degree with high mathematical / computing content, or equivalent commercial experience * Experience with GPU and CPU optimization technologies (for example, NUMA architectures or GPU profiling techniques) * Experience with C/C++, or other low-level or object-oriented languages * Experience building tools and technologies within systematic or discretionary investing units * Experience working with applied mathematics, financial markets and instruments, with awareness of underlying concepts Inclusion, Work-Life Balance and Benefits at Man Group You'll thrive in our working environment that champions equality of opportunity. Your unique perspective will contribute to our success, joining a workplace where inclusion is fundamental and deeply embedded in our culture and values. Through our external and internal initiatives, partnerships and programmes, you'll find opportunities to grow, develop your talents, and help foster an inclusive environment for all across our firm and industry. Learn more at www.man.com/diversity. You'll have opportunities to make a difference through our charitable and global initiatives, while advancing your career through professional development, and with flexible working arrangements available too. Like all our people, you'll receive two annual 'Mankind' days of paid leave for community volunteering. Our comprehensive benefits package includes competitive holiday entitlements, pension/401k, life and long-term disability coverage, group sick pay, enhanced parental leave and long-service leave. Depending on your location, you may also enjoy additional benefits such as private medical coverage, discounted gym membership options and pet insurance. Equal Employment Opportunity Policy Man Group provides equal employment opportunities to all applicants and all employees without regard to race, color, creed, national origin, ancestry, religion, disability, sex, gender identity and expression, marital status, sexual orientation, military or veteran status, age or any other legally protected category or status in accordance with applicable federal, state and local laws. Man Group is a Disability Confident Committed employer; if you require help or information on reasonable adjustments as you apply for roles with us, please contact TalentAcquisition@man.com.
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI. Your Impact We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible. As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow. What You Will Do * Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications. * Design strategy and build roadmaps for maturing the platform. * Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack. * Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R&D cycles. * Deliver high-quality and well-tested user-focused features. Skills and Qualifications Essential: * Proven experience in architecting and managing large-scale AI/ML workloads in a production environment. * Expertise in cloud compute design, specifically within Google Cloud Platform (GCP). * Orchestration: Significant experience deploying and managing complex workloads within Kubernetes (GKE). * Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute. * Strong programming skills and a "reliability-first" approach to software development. Nice to Have: * A career history that spans both ML Software Engineering and Infrastructure SRE roles. * Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment. * Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking. * Experience with Google TPU generations and specialized ML-driven R&D cycles. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs
Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI. YOUR IMPACT This is an exciting opportunity for versatile software engineers to be working in a fast-paced and research-facing environment within a small team. You will contribute significantly to a world-class ML-based software platform set to transform the bio-pharmaceutical world. We need creative thinkers ready to redefine how drugs are designed with the power of AI. Working in a highly creative, iterative environment, you will be partnering with leading engineers, scientists and ML researchers to build the critical platform driving that transformation. This is a newly created role and you will need to use your previous experience and show initiative in order to fully carve out your contribution. WHAT YOU WILL DO Depending on your experience and background, you can be expected to work on one or more of the following domains: * Software engineering of data services for data storage and integration layers * Ingestion, transformation and serving of scientific data for scientific applications * Building a state-of-the-art platform for conducting research with high velocity and reliability * Collaboration with scientist and ML researchers on project work SKILLS AND QUALIFICATIONS ESSENTIAL * Experience in data engineering and service-oriented architectures * Extensive software engineering experience with software design and architecture skills * Extensive enterprise programming experience writing production code using Python * Experience building, deploying, and maintaining secure and scalable production systems on GCP * Experience with Kubernetes and cloud computing * Demonstrated ability to work in multi-disciplinary teams and environments * Great degree of adaptability and a willingness to work across domains and different parts of the tech stack when needed * Demonstrate ongoing career progression / trajectory and a passion for learning * Msc in computer science, or equivalent experience NICE TO HAVE In addition to the essential qualifications listed above, we also expect successful candidates to have some of the following qualifications: * Experience with the management of scientific and experimental wet lab data in a pharma context * Experience with life sciences data, including bioinformatics, computational chemistry, and biomedical research data * Experience building backend systems for web applications, using technologies such as Django, SQLalchemy, Pydantic, PostgreSQL, DBT * Experience designing, implementing and maintaining relational data models with Python-based interfaces * Hands-on experience with cloud engineering in a compute-heavy environment, preferably on GCP CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs