PROMOTØR Trondheim

Researcher in synthetic biology and biosynthetic gene cluster expression

NTNU - Norwegian University of Science and Technology

This is NTNU​ NTNU is a broad-based university with a technical-scientific profile and a focus in professional education. The university is located in three cities with headquarters in Trondheim. At NTNU, 9,000 employees and 43,000 students work to create knowledge for a better world. You can find more information about working at NTNU and the application process here.     Video: https://youtu.be/Xt-yHCN5QS0About the Job​ We have a vacancy for a full-time three year researcher at the Department of Biotechnology and Food Science, NTNU. The position is linked to AIMARIA – Accelerating Innovation in Marine AI-Powered Bioprospecting, a Horizon Europe Innovation Action coordinated by NTNU.  AIMARIA combines omics, bioinformatics, artificial intelligence, synthetic biology, bioprocess development and sustainability assessment to accelerate the discovery and sustainable production of marine and aquatic natural products. At NTNU, a central part of the project is the development of more predictable and efficient methods for the refactoring and heterologous expression of biosynthetic gene clusters (BGCs).  The researcher will have a leading role in developing NTNUs experimental platform for BGC expression. The work will combine molecular biology, microbial strain engineering and synthetic biology with AI-supported design of regulatory DNA elements and expression constructs. The researcher will work closely with a PhD candidate recruited to the same scientific activity and with national and international partners in the AIMARIA consortium.  The position is well suited for a researcher who would like to develop and apply advanced synthetic-biology methods to challenging microbial expression systems and contribute to the production of biologically active natural products and enzymes.  Your immediate leader is Head of the department. Duties of the position​ • Develop and implement strategies for the design, refactoring and heterologous expression of biosynthetic gene clusters.  • Design and construct expression systems, including promoters, 5′ untranslated regions and other regulatory DNA elements.  • Engineer and evaluate microbial host strains for the expression of complex biosynthetic pathways.  • Analyse and interpret molecular, expression and production data.  • Coordinate relevant NTNU activities with partners in the AIMARIA consortium.  • Contribute to project deliverables, scientific reports, presentations and peer-reviewed publications.  • Present project results at consortium meetings, scientific conferences and relevant stakeholder events.  The distribution of duties may be adjusted according to the candidate’s qualifications and the scientific development of the project.  Required selection criteria​ • A completed PhD in synthetic biology, molecular biology, biotechnology, microbiology, biochemistry, biochemical engineering or another relevant discipline.  • Documented hands-on experience in BGC refactoring, molecular cloning, DNA assembly and genetic engineering of microorganisms.  • Experience with heterologous gene expression, metabolic engineering, pathway engineering or related microbial biotechnology.  • Ability to plan, conduct, document and analyse experimental research independently.  • Experience with the analysis and interpretation of biological data.  • A scientific publication record relevant to the position.  • Excellent written and oral English language skills.  The PhD degree must have been completed and documented by the application deadline.  Preferred selection criteria​ • Experience with biosynthetic gene clusters or microbial natural-product pathways.  • Experience with Streptomyces, actinomycetes or other microbial hosts used for heterologous BGC expression.  • Experience with assembly, manipulation or expression of large DNA constructs.  • Experience with promoter engineering, regulatory-sequence design or optimisation of microbial gene expression.  • Experience with CRISPR-based genome engineering or other advanced strain-engineering methods.  • Knowledge of bioinformatics, DNA-sequence analysis or computational design tools.  • Experience with high-throughput experimental workflows, automation or design–build–test–learn cycles.  • Experience with microbial cultivation, fermentation or bioprocess development.  • Experience with metabolite analysis or interpretation of LC–MS or related analytical data.  • Experience with supervision of students or junior researchers.  • Experience from international or externally funded collaborative research projects.  • Knowledge of research-data management, open science and FAIR data principles.  Personal characteristics​ • Scientifically curious and motivated to solve complex experimental problems.  • Able to work independently while contributing actively to a collaborative research environment.  • Structured, systematic and attentive to experimental documentation and data quality.  • Proactive and able to move work forward across several parallel activities.  • Able to communicate clearly with researchers from different scientific and professional backgrounds.  • Supportive and constructive in the supervision of students and junior colleagues.  • Flexible and comfortable working in a large international consortium.  In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience and personal suitability, as well as motivation, in terms of the qualification requirements specified in the advertisement.  We offer​ • Exciting and stimulating tasks in a strong international academic environment  • An open and inclusive work environment with dedicated colleagues  • Experience with coordination of a large EU-funded biotechnology and bioeconomy project.  • Favourable terms in the Norwegian Public Service Pension Fund • employee benefits Salary and conditions​ As a researcher (code 1109) you are normally renumerated depending on qualifications and seniority. As required by law, 2% of this salary will be deducted and paid into the Norwegian Public Service Pension Fund. The position is for a period of three years. The Researcher is expected to start during the autumn semester of 2026, although the precise start date can be agreed upon.  The engagement is to be made in accordance with the regulations in force concerning State Employees and Civil Servants, and the acts relating to Control of the Export of Strategic Goods, Services and Technology. Candidates who by assessment of the application and attachment are seen to conflict with the criteria in the latter law will be prohibited from recruitment to NTNU.    After the appointment you must assume that there may be changes in the area of work.  For the necessary professional and social interaction, it is a prerequisite that you are physically present and available to the institution on a daily basis.  About the application​ Your application and supporting documentation must be in English or a Scandinavian language. Please note:​ the application will only be assessed on the basis of the information we have received by the application deadline. Therefore, make sure that your application clearly shows how your skills and experience meet the criteria described above. The application and all attachments must be sent electronically via Jobbnorge.no. Applications submitted by other means will not be considerered. Please do not send separate application documents or additional information by e-mail.  If you are invited to an interview, you must bring certified copies of certificates and diplomas upon request. Your application must include: • CV, certificates and diplomas.  • A short application letter describing your motivation and relevant experience.  • A complete list of publications and other relevant scientific outputs.  • Copies of up to five scientific works that you consider particularly relevant to the position.  • A brief description of your contribution to the submitted scientific works.  • Names and contact information for three relevant referees.  • Documentation of the scope and quality of any education taken abroad. If you already have a statement from NOKUT/HK-dir, please attach this as well.  It is important that you both document and reflect on your competence. You are encouraged to use the NTNUs competence matrix as a guide for  documentation of your competence. Joint work will also be considered. If it is difficult to identify your specific input to a joint project, you must include evidence of your contributions.  In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience and personal and interpersonal qualities. Motivation, ambitions, and potential will also count in the assessment of the candidates. Open scientific practice will be recognized. NTNU is obliged by the evaluation criteria for research quality in accordance with The San Fransisco Declaration on Research Assessment – DORA and The obligations in the Coalition for Advancing Research Assessment ( CoARA) on responsible assessment of research and recognition of a wider range of academic contributions to science and society. This means that we will pay particular attention to the quality and academic range demonstrated by your scientific work to date. We will also pay attention to research leadership and participation in research projects. Your scientific work from the last five years will be given the most weight. Your application will be considered by a committee at the department. Candidates of interest will be invited to an interview. General information​ NTNU believes that inclusion and diversity is a strength. We want our faculty and staff to reflect Norway’s culturally diverse population and we continuously seek to hire the best minds. This enables NTNU to increase productivity and innovation, improve decision making processes, raise employee satisfaction, compete academically with global top-ranking institutions and carry out our social responsibilities within education and research. NTNU emphasizes accessibility and encourages qualified candidates to apply regardless of gender identity, ability status, periods of unemployment or ethnic and cultural background.  As an employee at NTNU, you must at all times adhere to the changes that the development in the subject entails and the organizational changes that are adopted.   A public list of applicants with name, age, job title and municipality of residence is prepared after the application deadline. If you want to reserve yourself from entry on the public applicant list, this must be justified. Assessment will be made in accordance with current legislation. You will be notified if the reservation is not accepted.  If you have any questions about the position, please contact Rahmi Lale, e-mail: rahmi.lale@ntnu.no. If you have any questions about the recruitment process, please contact Cecilie Skagfjord, e-mail: cecilie.skagfjord@ntnu.no.  If you think this looks interesting and in line with your qualifications, please submit your application electronically via jobbnorge.no with your CV, diplomas and certificates attached. Applications submitted elsewhere will not be considered. Upon request, you must be able to obtain certified copies of your documentation.     Application deadline: 09.08.2026​ The city of Trondheim is a modern European city with a rich cultural scene. Trondheim is the innovation capital of Norway with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality.

PhD Candidate in synthetic biology and biosynthetic gene cluster expression

NTNU - Norwegian University of Science and Technology

This is NTNU​ NTNU is a broad-based university with a technical-scientific profile and a focus in professional education. The university is located in three cities with headquarters in Trondheim. At NTNU, 9,000 employees and 43,000 students work to create knowledge for a better world. You will find more information about working at NTNU and the application process here.     Video: https://youtu.be/Xt-yHCN5QS0About the position​ We have a vacancy for a full-time PhD candidate at the Department of Biotechnology and Food Science, NTNU. The position is linked to AIMARIA – Accelerating Innovation in Marine AI-Powered Bioprospecting, a Horizon Europe Innovation Action coordinated by NTNU.   AIMARIA combines omics, bioinformatics, artificial intelligence, synthetic biology, bioprocess development and sustainability assessment to accelerate the discovery and sustainable production of marine and aquatic natural products. At NTNU, a central part of the project is the development of more predictable and efficient methods for the refactoring and heterologous expression of biosynthetic gene clusters (BGCs).   The PhD project will investigate how regulatory DNA elements, BGC architecture and microbial host selection influence the expression of complex biosynthetic pathways. Molecular biology, microbial strain engineering and synthetic biology will be combined with AI-supported design of promoters, 5′ untranslated regions and other regulatory elements. The resulting data will be used to establish more predictable design principles for BGC expression and to support iterative AI-guided design–build–test–learn cycles.  The precise scope of the doctoral project will be refined according to the candidate’s qualifications, the BGCs prioritised in AIMARIA and the scientific development of the project.   The PhD candidate will work closely with a researcher recruited to the same scientific activity and with national and international partners in the AIMARIA consortium. The project will provide training at the interface between fundamental research in microbial gene regulation and applied development of microbial production systems for marine natural products and enzymes.  The successful candidate will be admitted to the PhD programme in Biotechnology at NTNU (https://www.ntnu.edu/studies/phbiot ).The place of work is the Department of Biotechnology and Food Science in Trondheim.  Your immediate leader is Head of the department.  Duties of the position​ • Design and construct expression systems for heterologous expression of biosynthetic gene clusters.  • Assemble, modify and refactor BGCs and associated genetic constructs.  • Design and experimentally test promoters, 5′ untranslated regions and other regulatory DNA elements.  • Genetically engineer microbial host strains and evaluate their suitability for BGC expression.  • Conduct molecular-biology, microbiology and synthetic-biology experiments.  • Analyse BGC transcription, gene expression and product formation.  • Apply bioinformatic and AI-supported tools for the design and prioritisation of genetic constructs.  • Document, analyse and interpret experimental data.  • Collaborate with researchers and project partners responsible for BGC discovery, cell-free expression, analytical chemistry and bioprocess development.  • Participate in AIMARIA consortium meetings, scientific workshops and conferences.  • Publish results in peer-reviewed scientific journals and present the work in the doctoral thesis.  • Contribute to project deliverables and scientific reporting relevant to the doctoral work.  • Participate in the Department’s doctoral training and academic environment.  The primary responsibility of the PhD candidate is to conduct research leading to completion of a doctoral degree.   Be prepared for changes to your work duties after employment. Required selection criteria​ • A master’s degree or equivalent education in synthetic biology, molecular biology, biotechnology, microbiology, biochemistry, biochemical engineering or another field relevant to the project.  • Practical laboratory experience in molecular biology, microbiology, genetic engineering or related experimental methods.  • Ability to analyse, interpret and clearly document experimental results.  • Excellent written and oral English language skills.  • Motivation to undertake independent research and complete a doctoral degree.  • Your education must correspond to a five-year Norwegian course, where 120 credits have been obtained at master’s level. Master students can apply, but he master’s degree must be obtained and documented before starting in the position and not later than 01.01.2027.  • A strong academic background relevant to molecular biology, microbial genetics or synthetic biology, and have an average grade from your Master's degree study, or equivalent education, which is equal to B or better compared to NTNU's grading scale. If you do not have letter grades from previous studies, you must have an equally good academic foundation. If you have a weaker grade background, you may be considered if you can document that you are particularly suitable for a PhD education.  • You must meet the requirements for admission to the faculty's Doctoral Programme (https://www.ntnu.edu/phd)  PLEASE NOTE: For detailed information about what the application must contain, see paragraph “About the application”.  The appointment is to be made in accordance with NTNUs guidelines for recruitment positions for general criteria for the position. Preferred selection criteria​ • Experience with molecular cloning, DNA assembly or construction of expression vectors.  • Experience with genetic modification of bacteria or other microorganisms.  • Experience with heterologous gene expression or microbial strain engineering.  • Knowledge of biosynthetic gene clusters, secondary metabolism or microbial natural products.  • Experience with Streptomyces, actinomycetes or other microbial production hosts.  • Experience with CRISPR-based engineering or related genome-editing techniques.  • Knowledge of promoter engineering, gene regulation or regulatory DNA-sequence design.  • Experience with bioinformatics, sequence analysis, programming or computational biology.  • Experience with microbial cultivation, fermentation or bioprocessing.  • Experience with analytical methods used to investigate gene expression, proteins or metabolites.  • Experience with systematic experimental design or design–build–test–learn workflows.  Personal characteristics​ • Strong motivation for experimental research and doctoral training.  • Scientifically curious and willing to learn new methods.  • Able to work independently while seeking guidance when needed.  • Systematic, careful and attentive to experimental documentation and data quality.  • Persistent and constructive when experimental work presents challenges.  • Collaborative and comfortable working in an interdisciplinary and international environment.  • Able to communicate research clearly in writing and orally.  In the assessment of the best-qualified candidate, emphasis will be placed on education, academic performance, relevant experimental experience, motivation, scientific potential and personal suitability.  We offer​ • Exciting and stimulating tasks in a strong international academic environment  • An open and inclusive work environment with dedicated colleagues  • Experience with coordination of a large EU-funded biotechnology and bioeconomy project.  • Favourable terms in the Norwegian Public Service Pension Fund  As a PhD Candidate at NTNU, you will have access to employee benefits. Diversity​ Diversity is a strength, and at NTNU we aim to be an employer that reflects the diversity in society and that makes use of the potential of the population's collective skills. Our vision is Knowledge for a better world and our values ​​are creative, critical, constructive and respectful. We believe that an organization that is equal, diverse and gender-balanced is essential for us to achieve our goals.  We strive to attract employees with different skills, life experiences and perspectives to contribute to even better problem solving of our societal mission in research and education.  If you think this position is relevant and interesting, we encourage you to apply, regardless of gender, functional ability and cultural background, or whether you have been out of work for a period of time. Salary and conditions​ The gross salary for the position of 1017 PhD Candidate will normally be NOK 550 800,- per annum depending on qualifications and seniority. A 2% statutory contribution to the State Pension Fund is deducted from the salary.    The position is for a period of three years. The candidate is expected to start during the autumn semester of 2026, although the precise start date can be agreed upon.  For employment as a PhD Candidate, it is a prerequisite that you gain admission to the PhD programme in Biotechnology  (https://www.ntnu.edu/phd) within three months of your employment contract start date, and that you participate in an organized doctoral programme throughout the period of employment.  The position is conditional on external funding.  As an employee at NTNU, it is important that you keep yourself up to date with academic and organizational changes and adapt to them.  For the necessary professional and social interaction, it is a prerequisite that you are physically present and available to the institution on a daily basis.  The appointment is carried out in accordance with the principles of the State Employees Act, and Export control (legislation that regulates the export of knowledge, technology and services). Candidates who, after assessment of the application and attachments, are considered to be in conflict with the criteria in the latter act, will not be able to be employed.  After the appointment you must assume that there may be changes in the area of work.  It is a prerequisite you can be present at and accessible to the institution on a daily basis.  About the application​ The attachments (including a description of your scientific work) must accompany the application as these documents form the basis of the application assessment. The documents must be in Norwegian/a Scandinavian language or English Please note that applications will be assessed only on the basis of the information received by the application deadline. You should therefore ensure that your application clearly demonstrates how your skills and experience meet the criteria described above. The application and all attachments must be submitted electronically via Jobbnorge.no. Applications submitted by other means will not be considered. Please do not send separate application documents or additional information by e-mail.   The application must include: • CV, diplomas and certificates.  • A short application letter describing your motivation, research interests and suitability for the PhD project.  • Transcripts of grades from bachelor’s and master’s degree studies.  • A copy of the master’s thesis. Candidates who have not yet submitted their thesis may provide a draft or a short description of the work and expected submission date.  • Copies of publications or other scientific works, where applicable.  • Names and contact information for three relevant referees.  • Documentation of the scope and quality of education completed outside Norway, where applicable.  If all, or parts, of your education has been taken abroad, we also ask you to attach documentation of the scope and quality of your entire education, both Bachelor's and Master's education, in addition to other higher education. If your institution uses “diploma supplement” (normal for most European institutions), you must attach this. A description of the documentation required can also be found here. If you already have a statement from Norwegian Directorate for Higher Education and Skills (HK-dir), please attach this as well. Joint work will be considered. If it is difficult to identify your contribution to joint work, you must attach a brief description of your participation. In the evaluation of which candidate is best qualified, emphasis will be placed on education, experience, personal suitability and motivation in terms of the qualification requirements specified in the advertisement.  NTNU recognizes a wide range of academic contributions and has committed itself to The San Francisco Declaration on Research Assessment and CoARA (responsible assessment of research and recognition of a greater breadth of academic contributions in accordance with NTNU's social mission). General information​ A public list of applicants with name, age, job title and municipality of residence is prepared after the application deadline. If you wish to be exempt from entry on the public applicant list, this must be justified. Assessment will be made in accordance with current legislation. You will be notified if the exemption is not granted. If you think this position looks interesting and in line with your qualifications, you are welcome to apply. If you have any questions about the position, please contact Rahmi Lale, email: rahmi.lale@ntnu.no. If you have any questions about the recruitment process, please contact Cecilie Skagfjrod, e-mail: cecilie.skagfjord@ntnu.no. Application deadline: 09.08.2026​ ----------------- For practical information about working at NTNU, please visit this webpage.  The city of Trondheim​ is a modern European city with a rich cultural scene. Trondheim is the tech capital of Norway with a population of 200,000. The Norwegian welfare state, including healthcare, schools, kindergartens and overall equality, is probably the best of its kind in the world. Professional subsidized day-care for children is easily available. Furthermore, Trondheim offers great opportunities for education (including international schools) and possibilities to enjoy nature, culture and family life and has low crime rates and clean air quality.

PROMOTØR Drammen

Brand Impact

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