Principal Applied Scientist

Doctolib

WHAT YOU’LL DO We are looking for a Senior Staff Machine Learning Engineer to join the Clinical team in the AI and Machine Learning Department. You'll lead the technical direction of AI systems that enhance clinical decision-making and patient care. You'll tackle the hardest problems in healthcare AI, from building voice-powered consultation assistants to establishing LLM evaluation frameworks that ensure clinical safety and efficacy. This role combines deep R&D with strategic technical leadership, shaping how Doctolib deploys AI in regulated healthcare environments. Your responsibilities include but are not limited to: Technical Strategy & Architecture * Own the long-term technical roadmap for clinical ML systems, from model architecture selection to production deployment patterns * Drive strategic build vs. buy decisions, balancing custom development with foundation model APIs * Define standards for safe rollout in healthcare contexts: shadow testing, staged deployment, and human-in-the-loop workflows End-to-End ML Delivery * Lead design and implementation of LLM-powered clinical agents (consultation summarization, clinical coding, evidence-grounded recommendations) * Establish rigorous evaluation frameworks using real-world clinical datasets, ensuring outputs meet clinical accuracy and safety standards * Build production infrastructure: model and prompt versioning, guardrails, uncertainty quantification, cost optimization, and observability * Define a bold strategy for online and offline performance objectives to reach new levels of healthcare professionals satisfaction Leadership & Impact * Mentor Staff or Senior ML Engineers and Applied Scientists, elevating technical standards across the organization * Lead cross-functional initiatives spanning Product, Medical Affairs, Legal, and Compliance teams * Translate clinical needs into research questions and production systems that measurably improve patient outcomes * Partner with our medical, legal, and compliance teams to meet EU regulatory expectations (e.g., GDPR, MDR, upcoming EU AI Act) and market standards.   WHO YOU ARE Before you read on,  if you don't have the exact profile described below, but you feel this job description matches your skill set, we still encourage you to apply. * You have 10+ years in ML/AI with 3+ years at Staff+ or Principal level leading complex, multi-team technical initiatives * You have a PhD in Computer Science, AI, Statistics, or related field (or equivalent research experience) * You have deep expertise in at least two of: clinical NLP, LLM fine-tuning and evaluation, automatic speech recognition, RAG systems, or reinforcement learning * You are expert in Python, PyTorch/Transformers for training, vLLM/similar for inference with a track record deploying ML systems in production (AWS/GCP) * You have exceptional communication skills and are able to align diverse stakeholders and explain complex technical decisions Now it would be fantastic if you have: * Publications in top-tier ML/AI conferences (NeurIPS, ICLR, ACL) or medical informatics venues * Experience with EU healthcare regulations (GDPR, MDR, AI Act) * Prior work with clinical data or healthcare applications WHAT WE OFFER * Free comprehensive health insurance (basic package) for you and your children * 25 days of paid vacation per year, plus up to 14 days of RTT * Free mental health and coaching services through our partner Moka.care * Work from abroad for up to 10 days per year thanks to our flexibility days policy * Lunch vouchers (Swile card) worth €8.50 per working day, with €4.50 covered by Doctolib * A subsidy from the work council to refund part of the membership to a sport club or a creative class * 50% reimbursement of your public transport subscription * ParentCare Program: Enjoy full salary coverage (100%) during your first month of birth leave, and 75% during the second, covered by Doctolib * Enrollment in Doctolib's long-term employee value sharing plan called DoctoGrowth * For caregivers and workers with disabilities, a package including an adaptation of the remote policy, extra days off for medical reasons, and psychological support * Relocation support in case of international mobility * Access to the best AI tools for coding, development and dedicated training THE INTERVIEW PROCESS * HR Screen * Hiring Manager Interview * Behavioral Interview * Technical Questions  * Technical Case Study * At least one reference check   JOB DETAILS * Permanent position * Full-time * Hybrid work mode (3 days/week in the office) * Paris, France * Start date: as soon as possible   If you would like to find out more about tech life at Doctolib, feel free to read our latest Medium blog articles! At Doctolib, we are committed to improving access to healthcare for everyone. This translates into our recruitment process. We evaluate candidates based solely on qualifications and motivation, without any form of discrimination. The more diverse ideas are heard, the more our product will truly improve healthcare for all. You are welcome to apply to Doctolib, regardless of your gender, religion, age, sexual orientation, ethnicity, disability. To ensure equal opportunities, we invite you to exclude personal information (e.g. pictures, age) from your applications. If you require any accommodation, please let us know for support during the hiring process. Join us in building the healthcare we all dream of! All information provided is processed by Doctolib for application management. For data processing details, click here. Please contact hr.dataprivacy(at)doctolib.com for inquiries or to exercise your rights.   * *

Airbnb

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: We connect Airbnb’s community with the right information, in the right place, at the right time. We tailor Messaging & Notifications so hosts on Airbnb can streamline their operations, and travelers get just the information they need to enjoy their stay worry-free.     Additionally, we are building new connections within our community to help enrich the experience of hosting & traveling on Airbnb: easing the process of hosting, and adding meaning to our guest’s trips. The Difference You Will Make: We believe our current customer experiences in these domains are only scratching the surface of the innovations that are possible, and that science is at the heart of delivering a step-function change for our Guest and and Host on Airbnb.  You will architect and implement advanced machine learning solutions—including recommendation engines, ranking systems, intent detection models, and the integration of intelligence into existing platforms. Additionally, you’ll lead efforts to harness the power of Large Language Models (LLMs) to create transformative AI experiences. Many of the initiatives you’ll tackle are in their early conceptual stages. You will have the opportunity to shape these ideas from inception to production, turning visionary concepts into impactful realities. You will be leading ML, Data and Product engineers to drive ML applications.  A core focus of your work will be spearheading Machine Learning applications in Messaging and Notification—a high-impact area with significant potential to enhance guest and host experiences at Airbnb. A Typical Day:  * Envision, champion, and support the development of novel ML systems, product integrations, and performance optimizations to solve real-world problems * Lead, mentor, challenge and grow enthusiastic, collaborative software engineers and applied scientists across the organization * Raise the AI/ML skillset within the organization.  A passion for teaching/mentoring is important. Your Expertise: * 12+ years of software engineering experience, with 2+ years of experience in a Principal or Senior Staff Engineer role having ownership responsibility over large-scale software systems * Background in the design and development of scalable AI and ML systems and services, and a deep passion for building ML-powered products * You’re an inspiring colleague, a coach and mentor with experience owning and fostering engineering maturity in multiple organizations. * You’re a builder, and implementer, who seeks out high impact work, and who is: proactive, curious, and an excellent communicator Your Location: This position is US - Remote Eligible. The role may include occasional work at an Airbnb office or attendance at offsites, as agreed to with your manager. While the position is Remote Eligible, you must live in a state where Airbnb, Inc. has a registered entity. Click here for the up-to-date list of excluded states. This list is continuously evolving, so please check back with us if the state you live in is on the exclusion list. If your position is employed by another Airbnb entity, your recruiter will inform you what states you are eligible to work from. Our Commitment To Inclusion & Belonging: Airbnb is committed to working with the broadest talent pool possible. We believe diverse ideas foster innovation and engagement, and allow us to attract creatively-led people, and to develop the best products, services and solutions. All qualified individuals are encouraged to apply. We strive to also provide a disability inclusive application and interview process. If you are a candidate with a disability and require reasonable accommodation in order to submit an application, please contact us at: reasonableaccommodations@airbnb.com. Please include your full name, the role you’re applying for and the accommodation necessary to assist you with the recruiting process.  We ask that you only reach out to us if you are a candidate whose disability prevents you from being able to complete our online application. How We'll Take Care of You: Our job titles may span more than one career level. The actual base pay is dependent upon many factors, such as: training, transferable skills, work experience, business needs and market demands. The base pay range is subject to change and may be modified in the future. This role may also be eligible for bonus, equity, benefits, and Employee Travel Credits.   Pay Range $244,000—$305,000 USD

CoMind

At CoMind, we are developing a non-invasive neuromonitoring technology that will result in a new era of clinical brain monitoring. In joining us, you will be helping to create cutting-edge technologies that will improve how we diagnose and treat brain disorders, ultimately improving and saving the lives of patients across the world. THE ROLE: The Data Science team at CoMind develops the algorithms and machine learning systems that transform raw optical interference signals from CoMind One into continuous, clinically meaningful measurements of cerebral blood flow, intracranial pressure, and autoregulation. Working at the frontier of photonics, physiology, and applied ML, the team's work directly determines what CoMind One can measure, how accurately, and under what clinical conditions. As Principal Data Scientist, you will be the technical authority for CoMind's data science function, setting methodological direction for signal extraction and ML modelling, personally driving the most complex and highest-impact problems, and providing expert guidance across the team. This is a senior individual contributor role: you will not manage people directly, but your technical leadership will shape how the entire team approaches its most challenging problems. You will work closely with R&D, Clinical, and Software Engineering. At CoMind, all team members work at least 4 days per week from our new Kings Cross offices, plus a flexible work-from-home day. RESPONSIBILITIES: * Own the technical direction for signal processing and ML model development on CoMind One, defining approaches, architectures, and evaluation frameworks that set the standard for the team * Lead the development and validation of the most complex data science components, from novel algorithm design through to evidence generation for regulatory submissions * Act as the primary technical reviewer and expert resource across the data science team, setting the bar for methodological rigour, reproducibility, and scientific integrity * Drive the design and execution of data collection and labelling strategies with Clinical teams, including ground truth definition, dataset governance, and performance benchmarking * Contribute to CoMind's IP and publication strategy, authoring and reviewing technical papers, patent applications, and regulatory documents * Represent the data science function in cross-functional technical forums, architecture reviews, and external scientific and clinical engagements * Identify and introduce new methods, tools, and approaches that advance CoMind's signal extraction and ML capabilities * AI is fundamental to our culture. It's not just a tool, but a core part of how we work, collaborate, and innovate. We expect all team members to embrace AI in their daily work and continuously find new ways to use it effectively. SKILLS & EXPERIENCE: * 15+ years of experience in data science, ML, or applied research, with a strong track record of independent technical leadership on complex, ambiguous problems * Deep expertise in time-series signal processing and physiological or biomedical ML, including hands-on experience developing and validating models on noisy, real-world physiological data * Demonstrated ability to take algorithmic work from research through to production-quality, validated implementation * Experience in a regulated industry (medical devices, diagnostics, pharma, or similar), with familiarity with algorithm validation and documentation requirements for software as a medical device * Strong record of scientific output: publications, patents, or equivalent evidence of original technical contribution and domain authority Nice to Have * Background in neuroscience, neuromonitoring, neurophotonics, and/or cerebrovascular physiology * Experience with optical signal processing - e.g. LiDAR, pulse oximetry, NIRS, laser doppler flowmetry, or related technologies * Familiarity with FDA regulatory pathways for AI/ML-based medical devices BENEFITS: * Company equity plan so all employees share in the success of the company * Salary-sacrifice pension scheme * Private medical, dental and vision insurance (medical history disregarded) * Group life assurance at 4x annual income * Comprehensive mental health support, including unlimited access to 1:1 sessions with trained professionals * Unlimited holiday allowance (+ bank holidays) and one week of remote working per quarter * Lunch voucher (£10) every day for JustEat and free dinner on those days where you need to work later * Twice weekly deliveries of fresh fruit and an extensive selection of snacks and drinks * YuLife subscription, allowing you to turn your daily steps and meditation into discounts at a range of stores * Access to Udemy for upskilling and professional development.