
OGT · Oxford
OGT is a leading global provider of clinical and diagnostic genomic solutions. We believe in creating products and partnerships that enable clinicians to delive...
OGT is a leading global provider of clinical and diagnostic genomic solutions. We believe in creating products and partnerships
that enable clinicians to deliver personalised healthcare to patients and that empower clinical researchers to develop the next
generation of precision medicines.
An opportunity has arisen in our Oxford based Research & Development team for a Scientist II. Reporting to the Head of
Development, you will play an integral role in all aspects of new product development including laboratory preparation,
sequencing, bioinformatics, and data interpretation. You will have the opportunity to make a significant contribution to the
development of our NGS capabilities and portfolio.
This role is suited to someone who wants to perform lab-based research and innovative development work whilst working in a
commercial environment.
expand the product portfolio
Company
molecular approaches, design and development of molecular biology assays (NGS and others)
sequencing technologies
Application is via CV and a one-page covering letter outlining your suitability for the role, salary expectations and notice
period.
Please note that we will need to establish your right to work during the recruitment process.
ABOUT RELATION Relation is a sector defining TechBio company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure. We are scaling rapidly and building a team of exceptional individuals to push the boundaries of drug discovery. You will work in highly interdisciplinary teams where biology, computation, and engineering come together to solve complex problems that have not been solved before. Our state-of-the-art wet and dry labs in the heart of London are designed to accelerate this integration and translate insight into impact. We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the basis of gender, sexual orientation, marital or civil partnership status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. By joining Relation, you will help define how medicines are discovered and deliver meaningful impact for patients. THE OPPORTUNITY Relation is offering an outstanding opportunity for a Senior Scientist II / Principal Scientist, In Vivo Biology & Translational Science to help drive our growing discovery portfolio. We are looking for an experienced in vivo biologist with a strong track record of independently leading outsourced work packages through CRO partnerships and translating data into actionable project decisions, initially in support of our osteoporosis programme with scope to contribute across indications as the portfolio grows. In this role, you will own the design, delivery, and interpretation of in vivo pharmacology work packages, partnering closely with CROs and cross-functional colleagues across medicinal chemistry, biologics, DMPK, and safety. You will work at the intersection of experimental science and data-driven discovery within a growing TechBio company. DAY TO DAY, YOU WILL * Lead in vivo pharmacology strategy for projects within Relation's discovery programmes, proposing and championing the right study designs to support go/no-go decisions and milestone planning across multiple concurrent projects * Drive the execution, monitoring, and interpretation of in vivo pharmacology studies across target engagement, PK/PD, and disease-relevant efficacy endpoints * Own end-to-end CRO relationships for externally commissioned in vivo work packages: from vendor selection and SOW set-up through in-life liaison, data review, troubleshooting, and reporting * Commission in vivo-relevant in vitro and ex vivo assays, such as target engagement, pharmacodynamic, and mechanistic readouts, that directly inform study decisions and data interpretation * Translate biology data into clear, actionable insights and recommendations, communicating findings effectively to project teams and senior stakeholders * Maintain rigorous documentation standards across outsourced study packages, including ELN, protocol authoring and review, and study reporting * Champion Relation's collaborative, ambitious and science-driven culture, sharing scientific expertise across the team and helping to build an outstanding drug discovery organisation PROFESSIONALLY, YOU WILL HAVE * A PhD in Biology, Pharmacology, Biochemistry, or a related scientific discipline or equivalent experience in industrial drug discovery * Deep expertise in mammalian in vivo study design across target engagement, PK/PD, and efficacy endpoints, with the scientific judgement to define the right experiments to drive project decisions, a sound knowledge of 3Rs principles, and a proven record of delivering through CRO partnerships to quality and timeline * Experience commissioning or interpreting in vitro and ex vivo assays in support of in vivo programmes, including target engagement, pharmacodynamic, and mechanistic readouts * Experience across multiple stages of drug discovery (target ID through candidate selection) and across more than one disease area or physiological system * Scientifically rigorous and analytically critical, with the ability to interrogate data, challenge assumptions, and deliver across a broad and fast-moving project portfolio * Exceptional communication and stakeholder management skills: able to distil complex biology into clear project-level insights and influence cross-functional decisions * A deep passion for disease biology and drug discovery, with intellectual curiosity, enthusiasm for tackling complex scientific problems, and a drive to integrate emerging technologies with experimental science * Bonus experience: experience working across different drug discovery modalities, including small molecules and/or biologics; experience in a TechBio or AI-driven discovery environment. PERSONALLY, YOU * Are comfortable working in a matrixed environment, balancing multiple stakeholders and contributing effectively across teams. * Take ownership of your work, proactively seek opportunities to contribute, and enable others to do their best work. * Communicate openly and directly, give and receive feedback constructively, and handle challenging conversations with respect. * Actively seek out diverse perspectives, build strong working relationships, and contribute to shared goals across teams. * Embrace challenges with openness and resilience, set high standards for yourself, and strive to deliver meaningful outcomes. Working style & Culture at Relation At Relation, we operate in a matrixed, interdisciplinary environment, where impact is driven through collaboration across scientific, technical, and operational domains. We collaborate, and you will partner with colleagues across multiple teams and projects, contributing your expertise while aligning to shared company priorities. We work together and win together! The patient is waiting! Recruitment Agencies Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs.
About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here. We are seeking a data scientist with a strong background in experimentation and statistical analysis to help us improve and iterate on our experimentation platform. The successful candidate will play a key role in improving our experiment processes at scale, leveraging their expertise to drive innovation and help make sure that Pinterest users are receiving the most thoroughly data-driven features. With thousands of experiments running concurrently, the magnitude of our operations presents a significant opportunity for impact. If you possess a strategic mindset, proven experience in experimental design and analysis, and a passion for driving results, we invite you to join us in shaping the future of experimentation. What you’ll do:; * Comb through the literature in experimentation to identify potential methodologies that can improve parts of our platform where we have the biggest opportunities. * Make the process of setting up, running and evaluating experiments smoother and more repeatable for our platform users, ensuring that decisions are risk-aware and consistent * Write workflows to make our vast experimentation meta-data able to be leveraged by our team and outside of our team to better understand the experimentation landscape. * Consult with product data science teams to debug, design or improve their experiments and experimentation process. What we’re looking for: * PhD in a relevant field (stats, applied math, biostatistics, etc…) OR 2+ years of hands-on experience working as a data scientist or applied scientist. * Experience working directly on experimentation problems and an awareness of state of the art methodologies. * The ability to write clean, efficient, and scalable code that can be easily maintained and extended by other team members. * Proficiency in software development best practices, including version control systems such as Git, to ensure efficient collaboration, code management, and reproducibility in a data science environment. * Familiarity with workflow management tools such as Apache Airflow to create and schedule data pipelines, allowing for automated and reliable execution of machine learning workflows. In-Office Requirement Statement: * We recognize that the ideal environment for work is situational and may differ across departments. What this looks like day-to-day can vary based on the needs of each organization or role. * This role will need to be in the office for in-person collaboration 1-2 times/quarter and therefore can be situated anywhere in the country. Relocation Statement: * This position is not eligible for relocation assistance. Visit our PinFlex page to learn more about our working model. #LI-NM4 #LI-REMOTE At Pinterest we believe the workplace should be equitable, inclusive, and inspiring for every employee. In an effort to provide greater transparency, we are sharing the base salary range for this position. The position is also eligible for equity. Final salary is based on a number of factors including location, travel, relevant prior experience, or particular skills and expertise. Information regarding the culture at Pinterest and benefits available for this position can be found here. US based applicants only $114,297—$235,319 USD Our Commitment to Inclusion: Pinterest is an equal opportunity employer and makes employment decisions on the basis of merit. We want to have the best qualified people in every job. All qualified applicants will receive consideration for employment without regard to race, color, ancestry, national origin, religion or religious creed, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, age, marital status, status as a protected veteran, physical or mental disability, medical condition, genetic information or characteristics (or those of a family member) or any other consideration made unlawful by applicable federal, state or local laws. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. If you require a medical or religious accommodation during the job application process, please complete this form for support. By submitting this application, I certify that all information submitted in my application and throughout the hiring process is true, accurate, and complete to the best of my knowledge. I understand that any false statement, omission, or misrepresentation may disqualify me from employment consideration or result in termination if discovered after hire.
About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here. Pinterest brings millions of people the inspiration to create a life they love. Behind that experience is a complex infrastructure ecosystem that powers reliability, performance, measurement, and efficiency across the platform. As Pinterest grows, it’s increasingly important that we understand these systems clearly so we can make smarter decisions for both Pinners and the business. We’re looking for a Data Scientist to join our Infrastructure Data Science team. In this role, you’ll partner with engineering and cross-functional teams to make Pinterest’s infrastructure more measurable, intelligible, and actionable. Depending on the area, your work may span app performance, shopping infrastructure, metrics quality, infrastructure governance, or site reliability. You’ll help build the data foundations, measurement systems, and analytical frameworks that enable Pinterest to optimize core technical systems and make better product and infrastructure decisions. What you’ll do: In this role, you will partner closely with engineering and cross-functional teams to improve how Pinterest measures, understands, and optimizes its infrastructure: * Partner with engineering teams to define, measure, and improve the health, quality, and efficiency of Pinterest’s infrastructure systems. * Build and refine metrics, dashboards, and analytical frameworks that make complex technical systems more understandable and actionable. * Strengthen data foundations by improving metric definitions, auditing data quality, and contributing to pipeline and measurement improvements where needed. * Design and analyze experiments, investigations, and deep dives to quantify the impact of infrastructure changes on user experience, reliability, and business outcomes. * Translate ambiguous technical problems into clear analyses and actionable recommendations for engineering and platform partners. * Support high-priority investigations and decision-making related to infrastructure performance, reliability, cost, and measurement quality. * Identify opportunities to improve how Pinterest measures and optimizes infrastructure across a range of domains, such as performance, shopping infrastructure, governance, metrics quality, and site reliability. What we’re looking for: * Masters degree in a relevant field such as Statistics, Applied Math, Biostatistics, or equivalent experience. * Strong SQL and analytical programming skills, with experience working through messy, imperfect data and building reliable metrics and datasets. * Experience partnering on or contributing to production-ready data pipelines, measurement systems, or foundational data work that improves data quality and usability. * Solid foundation in experimentation and measurement, with the ability to design analyses, interpret results rigorously, and partner effectively with engineers and other cross-functional stakeholders. * Demonstrated ability to translate ambiguous problems into clear analytical workstreams and actionable recommendations. * Strong cross-functional communication skills, with the ability to explain technical findings clearly to engineering, product, and platform stakeholders. * Ability to operate independently, prioritize across both longer-term projects and fast-turn inbound requests, and drive work forward in a dynamic environment. * Curiosity and a builder mindset, with excitement for improving messy systems and creating more scalable, trustworthy measurement foundations. Relocation Statement: * We recognize that the ideal environment for work is situational and may differ across departments. What this looks like day-to-day can vary based on the needs of each organization or role. In-Office Requirement Statement: * This position is not eligible for relocation assistance. Visit our PinFlex page to learn more about our working model. * This role will need to be in the office for in-person collaboration 1-2 times/quarter and therefore can be situated anywhere in the country. #LI-NM4 #LI-REMOTE At Pinterest we believe the workplace should be equitable, inclusive, and inspiring for every employee. In an effort to provide greater transparency, we are sharing the base salary range for this position. The position is also eligible for equity. Final salary is based on a number of factors including location, travel, relevant prior experience, or particular skills and expertise. Information regarding the culture at Pinterest and benefits available for this position can be found here. US based applicants only $114,297—$235,319 USD Our Commitment to Inclusion: Pinterest is an equal opportunity employer and makes employment decisions on the basis of merit. We want to have the best qualified people in every job. All qualified applicants will receive consideration for employment without regard to race, color, ancestry, national origin, religion or religious creed, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, age, marital status, status as a protected veteran, physical or mental disability, medical condition, genetic information or characteristics (or those of a family member) or any other consideration made unlawful by applicable federal, state or local laws. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements. If you require a medical or religious accommodation during the job application process, please complete this form for support. By submitting this application, I certify that all information submitted in my application and throughout the hiring process is true, accurate, and complete to the best of my knowledge. I understand that any false statement, omission, or misrepresentation may disqualify me from employment consideration or result in termination if discovered after hire.