
Bioptimus · Paris / Remote EU
Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovation in biomedicine. With more t...
Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate
innovation in biomedicine. With more than $75M in funding, Bioptimus is a fast-growing start-up headquartered in Paris,
incorporated in October 2023. Backed by leading international venture capitalists, our world-class team of scientists and
engineers is redefining the frontiers of AI and life sciences.
Bioptimus’ mission is to accelerate biomedical innovation by building the reference foundation model of biology that will unlock
AI superpowers for the biomedical ecosystem. As a well-funded and fast-growing start-up headquartered in Paris and incorporated in
October 2023, we are growing a world-class team of scientists, engineers, and product leaders.
This is a remote role. We’re headquartered in Paris, but the position can be performed remotely outside of Paris.
We are looking for a technical, execution-focused Clinical Data Manager to bridge the gap between unstructured, real-world data,
and our frontier AI models. In this role, you will be the authority on clinical data structures, serving as the technical link
during conversations with our global partners to standardise and harmonise data pipelines.
Operating within our STELA program, you will structure our clinical datasets. You are a hands-on technical expert who writes
reproducible code, enforces incoming data QC, and designs the data dictionaries and ontologies for our models.
We recently launched the Spatial Tissue Embedding Learning Atlas (STELA)—a multinational spatial data generation initiative
anchored by strategic partnerships with 10x Genomics and Broad Clinical Labs. STELA serves as the data backbone for M-Optimus,
aiming to profile up to 100,000 patient specimens across three continents (US, Europe, and Asia). This will integrate
high-resolution spatial transcriptomics, histopathology imaging, and longitudinal clinical records to bring forward the next era
of biological AI and precision medicine.
As our Clinical Data Manager, you will operate at the intersection of data engineering, clinical science, and partner
institutions, CROs/CMOs). Dive into the details of diverse clinical data structures to understand how data is captured, stored,
and extracted.
with an emphasis on clinical oncology and immunology data.
STELA’s multimodal pipeline requirements, while ensuring integration with existing pipelines.
incoming partner data for integrity, completeness, and programmatic consistency.
understand the gaps between ideal protocols and messy clinical realities, and you know what red flags to look for in incoming
data.
Actively audit data to find missing variables, anomalies, and hidden biases.
longitudinal treatment lines like immunotherapy vs. chemotherapy) so you can recognize what data is important.
The successful candidate will have a ‘team-first’ attitude; be independent, curious, and detail-oriented; thrive in a dynamic,
fast-paced environment; and be fun to work with. You possess the rare ability to confidently lead complex technical alignment
meetings with partners while simultaneously being excited to roll up your sleeves and write code.
Statistics, or a related quantitative field. Equivalent practical industry experience is highly valued.
engineering within a CRO, CMO, pharma, or biotech environment. Proven track record of taking messy partner data and building
reproducible, production-grade workflows.
manipulation, cleaning, and validation.
and building reusable data pipelines.
and longitudinal clinical trial data.
cancer/oncology and/or immunology datasets.
be defined from scratch.
To be considered, please submit your CV in English. We believe in a transparent and collaborative interview process. Here is what
more detail.
1. Data Strategy Panel Presentation (45 min): You will present a short overview of a past data management challenge you
overcame (e.g., designing a complex data dictionary or aligning messy CRO data), followed by Q&A.
2. Technical Deep Dive (30 min) - There will be 1 additional break out session to do a deep dive with 1-2 Bioptimus Engineers
3. Executive Interview (30 min): A discussion with member(s) of our Senior Leadership focusing on long-term vision, cultural
fit, and mutual potential.
contingent upon the successful completion of a reference check.
We believe that the unique contributions of all Bioptimists create our success. To ensure that our culture continues to
incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender
identity or expression, sexual orientation, age, or marital, or disability status. Decisions related to hiring are made fairly,
and we provide equal employment opportunities to all qualified candidates. We take responsibility for always striving to create an
inclusive environment that makes every employee and candidate feel welcome.
Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovation in biomedicine. With more than $75M in funding, Bioptimus is a fast-growing start-up headquartered in Paris, incorporated in October 2023. Backed by leading international venture capitalists, our world-class team of scientists and engineers is redefining the frontiers of AI and life sciences. THIS IS A REMOTE ROLE. WE’RE HEADQUARTERED IN PARIS, BUT THE POSITION CAN BE PERFORMED REMOTELY OUTSIDE OF PARIS. THE OPPORTUNITY We are looking for a Clinical Expert to support Bioptimus’ clinical and scientific strategy for digital twin and data generation programs. In this role, you will work closely with the science, data, and partnerships teams to support clinical prioritization, scientific interpretation, academic collaborations, and pharma engagement across our research programs. You will contribute clinical and translational expertise to help identify the most important clinical questions and modalities to focus on, support the interpretation of model outputs, and advise on partnerships and research programs aligned with Bioptimus’ data and scientific goals. This is a part-time engagement with the possibility of becoming full-time. WHAT YOU'LL BE DOING As a Clinical Expert, you will own the following tasks: * Clinical Strategy: Support the identification of the most important clinical questions and modalities to prioritize across training and validation cohorts. Provide clinical input on tissue, drug class, disease, and modality prioritization. Support the selection of clinical metadata, endpoints, and patient-level annotations required to maximize downstream model utility. Identify and prioritize clinically relevant tasks including response prediction, toxicity prediction, biomarker discovery, indication expansion, and trial enrichment. * Scientific Interpretation: Provide clinical and biological review of model outputs and scientific results. Work closely with the science team to support results review and contribute to external-facing scientific narratives. Translate model behavior into clinically credible language for pharmaceutical, key opinion leader, and regulatory audiences. * Data & Academic Partnerships: Support connections with academic investigators running relevant clinical studies, including early-phase studies, novel-agent programs, immuno-oncology programs, and multimodal cohorts. Advise on academic partnership structures that align research collaborations with Bioptimus’ data needs, including retrospective and prospective studies. * Pharma Engagement: Support discussions with pharmaceutical R&D teams where relevant. Advise on the positioning of model claims for translational medicine and clinical development audiences. WHAT YOU'LL BRING The successful candidate will bring deep clinical and translational expertise, strong scientific judgment, and enthusiasm for working in a collaborative and fast-paced environment. We value individuals who combine clinical research experience with genuine interest in emerging machine learning approaches in biology. * Clinical Research Experience: MD/PhD with active or recent Principal Investigator experience designing and analyzing clinical studies, particularly studies involving translational endpoints, biomarker sub-studies, and multimodal cohorts. * Onco-Immunology Expertise: Deep expertise in onco-immunology, including IO mechanisms, response and resistance biology, tumor microenvironment biology, IO combinations, and understanding of pharmaceutical pipelines and unmet clinical needs. * Machine Learning & Multimodal Biology Interest: Working understanding of and genuine interest in machine learning and foundation model approaches applied to pathology, transcriptomics, and multimodal data integration. * Collaboration & Communication: Ability to work closely with scientific, clinical, and external stakeholder groups. Strong communication skills with the ability to contribute to scientific discussions and external-facing narratives. Comfortable operating in a startup environment with ambiguity and evolving priorities. HOW TO STAND OUT: * Pharma R&D experience through an industry role or substantive pharmaceutical collaboration history. * Existing academic or hospital network in onco-immunology. * Experience designing and analyzing studies involving translational endpoints, biomarker sub-studies, or multimodal cohorts. * Familiarity with ML or foundation model approaches in pathology, transcriptomics, or multimodal biology. THE CANDIDATE JOURNEY To be considered, please submit your CV in English. We believe in a transparent and collaborative interview process. Here is what you can expect after submitting your application: 1. Screening: Once you have applied, the hiring team will review your application to determine if your work experience and skills align with the necessary proficiencies of this position. 2. Hiring Manager (30 min): A discussion with the Hiring Manager focused on your clinical and translational research background, scientific expertise, and motivation for collaborating with Bioptimus. 3. Strategic Case Study Discussion (60 min): A collaborative discussion with members of the scientific and technical teams focused on clinical strategy, translational medicine, multimodal biology, and the application of foundation models in oncology and immunology. 4. Offer: Following the completion of the interviews, our hiring team will make a final decision and will be in touch to share the outcome of your interviews. If the team would like to move forward, the recruiter will discuss the details of our proposed offer with you. 5. Onboarding: We are happy to have you joining the team. Once you have accepted and signed your offer, we will be in touch to begin the process of onboarding you to Bioptimus. WHY THIS IS A UNIQUE OPPORTUNITY * Be part of a trailblazing team working at the intersection of AI, biotech, and biomedical research. * Take on a high-impact leadership role, shaping the future of biomedical AI through strategic data partnerships. * Work in a collaborative, innovation-driven environment with top researchers and industry experts. We believe that the unique contributions of all Bioptimists create our success. To ensure that our culture continues to incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender identity or expression, sexual orientation, age, or marital, or disability status. Decisions related to hiring are made fairly, and we provide equal employment opportunities to all qualified candidates. We take responsibility for always striving to create an inclusive environment that makes every employee and candidate feel welcome.
ABOUT US Our mission at Avelios is to unlock clinical data to power seamless healthcare operations for better patient care. To do so, we have built a modular software platform that digitizes and optimizes workflows in hospitals with cutting-edge technology in a user-friendly way. With our software, we enable hospitals, doctors & nurses to provide their patients with the best possible care. We are growing fast and want to keep expanding our team and business to fundamentally digitize healthcare for the better. We appreciate different backgrounds and see diversity as one of our strengths. THE TEAM AND YOUR ROLE To further shape the future of healthcare, we are looking for a (Senior) Sales Manager (all genders) who will actively drive our sales pipeline and help expand Avelios’ impact across the clinical sector. In this role, you play a key part in growing our customer base and ensuring that hospitals across Germany benefit from our software platform. You will work closely with Marketing, Business Development, Product, and Customer Success to manage the entire sales cycle — from identifying and qualifying prospects to closing deals and supporting long-term customer relationships. This role offers a unique opportunity to help shape the commercial strategy of a fast-growing health-tech company and make a meaningful contribution to improving healthcare delivery. YOUR TASKS * Taking full ownership of the entire B2B sales process — from first contact to contract signature * Working closely with internal teams to ensure a seamless sales experience and successful implementation * Qualifying leads, advising potential customers, and converting them into long-term, satisfied partnerships * Developing tailored proposals that align customer needs with Avelios’ business objectives * Creating and refining sales strategies, presentations, and market analyses to expand the pipeline * Building and maintaining a strong network within the healthcare and hospital ecosystem * Tracking and reporting key sales KPIs to continuously improve forecasting and sales processes * Acting as a trusted point of contact for prospects and customers, clearly communicating product value to diverse stakeholders YOUR QUALIFICATIONS * Completed degree in business, engineering, medicine, or a comparable field * Strong experience in B2B software sales — ideally in healthcare or the hospital environment * Proven track record of acquiring new customers and driving measurable commercial impact * Excellent presentation and negotiation skills across different audiences * Strong interest in digital health and solid technical understanding of software products * Structured, solution-oriented mindset with strong execution capability * Independent, hands-on working style and enthusiasm for driving customer success * Fluent German skills and very good English skills YOUR BENEFITS * Variety in your tasks and the opportunity to take ownership * An international, informal team structure in a motivating start-up atmosphere, allowing you to participate directly in our customer growth story and the overall success of Avelios * Ability to gain valuable hands-on experience in a startup backed by leading international VCs * Support for your personal development through continuous learning and feedback * Set your own rhythm with flexible working hours and trust-based time tracking * A virtual stock option package (VSOP) that lets you participate in Avelios’ long-term value creation * A monthly meal allowance up to 75 euros, full coverage of the Deutschlandticket, Urban Sports Club or a subsidized Wellpass membership, a bike leasing program and Corporate Benefits that give you access to discounts from a wide range of providers in various areas
ABOUT US Our mission at Avelios is to unlock clinical data to power seamless healthcare operations for better patient care. To do so, we have built a modular software platform that digitizes and optimizes workflows in hospitals with cutting-edge technology in a user-friendly way. With our software, we enable hospitals, doctors & nurses to provide their patients with the best possible care. We are growing fast and want to keep expanding our team and business to fundamentally digitize healthcare for the better. We appreciate different backgrounds and see diversity as one of our strengths. THE TEAM AND ROLE As a Senior Product Manager (all genders) you will take end-to-end responsibility for the product strategy and further development of our core product areas within the Avelios platform — from discovery to delivery to rollout. You will work closely with Engineering, Design, our Medical team, customers, and partners, translating market and user needs into scalable, robust product features. This is a hands-on, high-impact role where product thinking meets digital transformation in healthcare. YOUR RESPONSIBILITIES * Own and continuously evolve the roadmap for a dedicated module within Patient Treatment and Billing, balancing customer commitments, regulatory requirements, and strategic product progress * Turn clinical user needs and market signals into clear product decisions by defining problem statements, outcomes, epics, user stories, and measurable acceptance criteria—so teams can build robust workflows that fit everyday clinical practice * Proactively orchestrate customer and regulatory input across discovery, specification, and prioritisation, ensuring medical correctness and practical usability are embedded in new development * Drive cross-functional alignment with Engineering, Design, and Implementation to enable predictable delivery: clarify scope, dependencies, and handovers; improve planning reliability; and raise quality and efficiency for the components you own * Plan and execute launches and enablement for your features by coordinating release readiness (documentation, training, internal roll-out prep), maintaining crisp stakeholder communication, and supporting go-to-market activities with the commercial and delivery teams YOUR QUALIFICATIONS * Degree in a business or technology-related field, e.g. Computer Science, Medical Informatics or a comparable field * 5+ years of product management experience in B2B SaaS or enterprise startups * Proven excellence in product management processes: structured discovery, data-driven prioritisation, and reliable delivery * Strong analytical and decisive working style with a systematic problem-solving approach * Demonstrated ability to manage multiple initiatives in parallel and align diverse stakeholders * Solid technical understanding of APIs, data flows, and system integrations is a plus * Passion for intuitive, modern digital products in healthcare * Fluency in English (spoken and written) YOUR BENEFITS * Variety in your tasks and the opportunity to take ownership * An international, informal team structure in a motivating start-up atmosphere, allowing you to participate directly in our customer growth story and the overall success of Avelios * Ability to gain valuable hands-on experience in a startup backed by leading international VCs * Support for your personal development through continuous learning and feedback * Set your own rhythm with flexible working hours and trust-based time tracking * A virtual stock option package (VSOP) that lets you participate in Avelios’ long-term value creation * A monthly meal allowance up to 75 euros, full coverage of the Deutschlandticket, Urban Sports Club or a subsidized Wellpass membership, a bike leasing program and Corporate Benefits that give you access to discounts from a wide range of providers in various areas