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Associate researcher in lung transplantation

Lunds universitet
  • OrtLund
  • OmfattningHeltid
  • Sista ansökan30 dagar kvar
  • Publicerad20 okt.

Om tjänsten

Description of workplace The research is conducted at the Biomedical Centre (BMC) in Lund, near Skåne University Hospital. It is

carried out within the Department of Clinical Sciences at Lund University, under the leadership of Associate professor Sandra

Lindstedt. The focus lies on clinically oriented research concerning lung transplantation related research, post-transplant

complications and lung regeneration. Within our research group, we prioritize a good working environment based on mutual respect

and care. We strive to create a workplace that is perceived as stimulating and conducive to both personal and professional

development. We continuously work to foster a sense of joy, engagement, and inclusion among all team members, ensuring both

physical safety and a supportive psychosocial work environment. We offer Lund University is a governmental authority, which means

you get special benefits, generous holidays, and a favorable occupational pension. Read more on the university's website about

being employed at Lund University, Work at Lund University We are seeking a driven and highly motivated Associate researcher with

the ability to work independently and further develop ongoing research projects. The position is full-time. The suggested start

date is January 1, 2027, or as agreed upon. Work description The duties at the research unit primarily consist of laboratory-based

research, with a particular focus on cell culture, cell isolation, and gene therapy. The successful candidate will primarily work

on a research project investigating the reactivation of developmental signaling pathways in lung disease, with a particular focus

on lung tissue repair and regeneration. The research will employ a combination of in vitro, ex vivo, and in vivo approaches. The

position has a strong translational focus, bridging experimental/preclinical research and clinical medicine, primarily within the

fields of thoracic surgery and pulmonary medicine. The main responsibilities include:

  • Independently designing, planning, and

conducting research within the project, as well as collecting, analyzing, interpreting, and managing data generated throughout the

project. - The project involves advanced CRISPR/Cas9 genome editing, including tissue processing, protocol development and

optimization, troubleshooting, and subsequent analysis and quantification. - The work will also involve the isolation of cells

from tissue and the characterization of both primary and commercially available cells, including analyses of proliferation,

migration, immunocytochemistry (ICC), and related cellular functions. - The position also includes responsibility for preparing

high-quality scientific manuscripts for publication in international peer-reviewed journals. - The majority of the work will be

conducted independently, while also involving close collaboration with both internal and external members of the research team and

other collaborators. - In addition, the position includes mentorship and supervision of postdoctoral researchers, PhD students,

and Master's students. Basis for assessment This is a merit-based position primarily focused on research. The position is intended

as an initial step in the academic career, and the selection will be based primarily on scientific merit and potential as a

researcher. Particular emphasis will be placed on demonstrated scientific skills within the subject area. For postdoctoral

appointments, the following shall form the basis for assessment: - Proven ability to develop and conduct high-quality research -

Teaching and pedagogical ability Additional qualifications will be assessed based on the following requirements for the position:

  • PhD degree (or equivalent) in biochemistry, bioengineering, or cell and molecular biology. - Technical proficiency and

scientific creativity in one or more of the following areas: lungtransplantation, large animal models, CRISPR and / or cell

modification. - Background in translational work, lung transplant and large animal models. - Experience with standard cellular and

molecular biology techniques, including Western blotting, ELISA, mass spectrometry, qPCR, immunohistochemistry, and HPLC. -

Experience in the isolation, culture, and differentiation of primary cells. - Experience with CRISPR/Cas9 genome editing of

primary cells, including mesenchymal cells. The research project is interdisciplinary, therefore candidates with a broad

competence profile spanning theses different areas are of special interest. Meritorious qualifications:

  • Ability to run and

coordinate interdisciplinary collaborations. - Good written and verbal communication skills. - Ability to carry out independent

and high-quality research as documented through peer-reviewed publications. - Documented Experience in mentoring and/or

supervision. - Good knowledge of clinical and translational lung transplantation. - Developed gen modified cells for large animal

models in lung transplantation. - Hands-on experience of handling samples from patients and large animals. - We look for a

candidate that is highly motivated, positive and independent. Eligibility Appointment to a post-doctoral position requires that

the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position. This

eligibility requirement needs to be met no later than the time when the employment decision is made. We will mainly consider

candidates who have completed their PhD degree no more than three (3) years before the last date for applications. Under special

circumstances, the doctoral degree can have been completed earlier. These circumstances refer to leave due to illness, parental

leave, clinical work, positions of trust within trade union organizations or other similar circumstances. Terms of employment This

is a full-time employment limited to 2 years. Preliminary start is the 1st of January 2027, or according to agreement. The period

of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on

fixed-term employment as a post-doctoral researcher”) between SACO-S, OFR/S and SEKO, dated November 19, 2021. How to apply The

position is sought via the university's recruitment system. The application must include a personal letter (maximum two pages) in

which you describe how you meet the qualification requirements and why you are interested in the position and how your research is

connected to the COMBAT project. The application must also contain a CV, including a list of publications, a general description

of previous research work (maximum one page), a copy of the doctorate and anything else you wish to refer to (copies of diplomas,

grades, information for references, letters of recommendation, etc.) as well as contact information for two references.

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