Security Engineering Manager, London or Lausanne

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   YOUR IMPACT  As a Senior AI Security Engineer at Isomorphic Labs, you will operate at the absolute frontier of Artificial Intelligence and Cybersecurity. Reporting directly to the CISO, your mission is to architect, secure, and future-proof our pioneering AI-first platform and autonomous agentic workflows that drive the next generation of drug discovery pipelines. In this high-impact role, you will design custom risk management frameworks tailored to the unique threat landscape of AI in life sciences, establish strict governance over critical model artifacts, and embed seamless security controls directly into distributed training and inference infrastructure. You will serve as the technical anchor bridging machine learning engineering, platform architecture, and adversarial defense. Operating in a fast-moving, high-stakes environment, you will lead AI-specific incident response and pioneer model-driven defense mechanisms to automate threat hunting and mitigation. Your work will ensure that breakthrough scientific research is paired with an uncompromising, resilient defense safeguarding invaluable intellectual property while accelerating our innovation velocity. WHAT YOU WILL DO * Adversarial Threat Modeling: Conduct cutting-edge threat modeling focused on AI/ML vulnerabilities, engineering a comprehensive risk management framework tailored to an AI-powered life sciences platform. * Model Artifacts Protection: Partner with AI teams to establish a granular inventory, classification and protection framework for ML models’ weights, code, and training data. * Agentic AI & LLM Guardrails: Design and deploy scalable guardrails, robust sandboxing, and real-time monitoring controls for our extensive LLM ecosystem, including ADK, MCP, and autonomous agentic workflows. * Collaborative Security Engineering: Partner with ML researchers and platform engineers to design and implement robust security controls across the entire ML lifecycle—from data ingestion and training pipeline integrity to inference runtime controls. * Model-Driven Incident Response: Act as the primary technical expert for AI security incidents, deploying advanced machine learning techniques to automate threat hunting, anomaly detection, and signatureless mitigation specific to LLMs. * Compliance & Governance Automation: Bridge the gap between complex AI architectures and emerging global regulations (e.g., EU AI Act) by automating risk posture monitoring and continuous compliance metrics. * AI Safety Frameworks: Pioneer the practical implementation of Isomorphic Labs' AI Safety standards, working in close coordination with Legal, Compliance, and external partners like Google DeepMind.   SKILLS AND QUALIFICATIONS  ESSENTIAL * AI/ML Engineering: Deep conceptual and practical understanding of deep learning frameworks (e.g., JAX, PyTorch, TensorFlow), large-scale cloud training or inference infrastructure, and LLM ecosystems. * Adversarial ML Mindset: Strong familiarity with AI security threat vectors (prompt injection, model inversion, data poisoning) and frameworks like OWASP Top 10 for LLMs or MITRE ATLAS. * Agentic Frameworks Security: Proven experience securing agentic frameworks (ADK, MCP), agentic first infrastructure and implementing robust agent-to-agent (A2A) identity and access controls. * Infrastructure Security: Solid proficiency in cloud platform security (GCP preferred), including container security, multi-cloud/SaaS integrations, and strict network isolation boundaries. * Pragmatic Risk Assessment: Proven ability to define and execute pragmatic mitigation strategies that balance a rigorous security posture with the high-velocity needs of a world-class scientific research organization. * Software Development & Automation: Ability to write production-grade code (Python preferred) to build custom security tooling, automate telemetry collection, or enforce policy layers. * Translational Communication: Exceptional skills in navigating ambiguity, building trusted relationships with AI researchers, and clearly translating complex machine learning risks into actionable engineering tasks for leadership. NICE TO HAVE * AI Red Teaming: Experience conducting empirical vulnerability research or executing simulated attacks against LLMs, agent networks, and core ML backends. * Regulated Environments: Prior exposure to BioTech, Pharma, and/or Deep Tech industries where data integrity, intellectual property protection, and regulatory compliance (GxP) are paramount. * Education & Background: BSc, MSc, or PhD in Computer Science, Machine Learning, Cybersecurity, or a related quantitative field. * Advanced Certifications: Relevant security or cloud credentials (e.g., OSCP, Professional Cloud Security Engineer) or specialized training in ML security. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

ClearBank

Grow with the challenge At the time of inception, cloud-based systems and API fluency were new. But that didn't scare us. We waved goodbye to legacy systems and embraced modern technology – where our true innovation began and didn't stop. No hierarchy, no egos. Just a spirit of collaboration that flows right throughout our organisation – it’s woven into our DNA. We genuinely want to know about each other’s learnings and expertise, especially where it can help us achieve bigger things. At ClearBank, we make things happen. We solve problems together because we know that many heads are always better than one. Valuing different perspectives is what sets our culture apart. And being able to disagree and commit is key to our progress. Above all we’re a team because when we win together, it feels so much better than doing it alone. What you can expect: ClearBank is a place where you can do things differently and challenge the status quo. We will give you a high level of autonomy and transparency, and we trust you to make the right decisions for the bank. If that excites you, how about joining our Security Engineering team as a Security Engineer, reporting to the team’s Engineering Manager. The team are responsible for reducing the likelihood and impact of cyber risks for ClearBank and drive adoption of security best practice. As a cross-cutting concern, we are involved with all major initiatives across the business. We also work closely with technology leadership to ensure security is woven into all processes. We are a remote-first team with members all over the UK. ClearBank is committed to harnessing cutting-edge technologies, such as AI, AKS, automation and scalable solutions, to secure a competitive edge in the marketplace. Our responsibility is to ensure these innovations are adopted securely, enabling the business to move forward safely. The security engineering team works with software development teams to improve application security and provides security oversight and support to many other areas of the business. We work alongside four other security teams who cover Identity Access Management, Security Operations, Governance and Compliance, and Data Privacy. Our team won the Best Implementation of DevSecOps at the Computing DevOps Excellence Awards 2024, and Most Effective DevSecOps Team of 2023). Your role includes: * Working alongside other security engineers to gain familiarity with the organisation’s processes and technologies. * The opportunity to build your skills in AI security, application security, and to keep up to date with the latest technology. * Collaborating with software development and platform teams to help them to deliver and maintain secure products using modern technologies. In the process you will build credibility and trust with them. * Championing security best practices and running security consultations / training sessions. * Trialling new technologies and pave the way for their adoption * Supporting existing security tooling and evaluating new tools as they become available. * Risk-based vulnerability management, taking a pragmatic approach to balancing security, customer, and business needs. Communicating these risks to the business. What you’ll bring: * To excel in this role, you’ll also need: * Experience in writing code and working in a cloud native environment. ClearBank primarily uses Azure, .NET, Terraform, and Kubernetes, so experience with these (or equivalent technologies) is beneficial. * Adaptability and commitment to continuous learning and self-development. * Great communication skills so that you can clearly articulate security risks and improvements to a variety of stakeholders around the business. * Good security knowledge and enthusiasm for software security. * Understanding of common software vulnerabilities and the ability to describe them to different audiences. Awareness of the wider security landscape. * Be a motivated team player who is delivery focused and can suggest solutions as to how things can be done better. Nice to have: * Experience in a fintech environment or similar upscale organisation. * Experience working with AI security and governance and leveraging the latest technology to stay ahead of the attackers. Regretfully we are not able to sponsor applicants for immigration purposes at the current time. What makes a great ClearBank team member? Does this sound like you? * You focus on solutions and positive outcomes, thinking radically and responsibly to find the best result for our customers, your colleagues and the bank. * You actively seek feedback from others to drive your growth and development, always assuming positive intent from others and develop strong, trusting relationships with your colleagues and customers; you really, genuinely care. * You always strive for the highest quality, but you know that done is better than perfect. You welcome a challenge knowing that you will learn as you go and iterate. * ‘I’ before ’we’, isn’t in your vocabulary A little bit more about us!  ClearBank is Where You Can belong:  At ClearBank we think about Diversity, Equity and Inclusion (DE&I) a lot. Not because we think we should. But because we know we should – how else can we build a happy workforce and be successful as a business. We’re committed to making sure our teams reflect society. And we put energy and effort into making this a place where everyone feels at home, where they’re given the trust and encouragement to do their very best work. Here are some of the things we’re most proud of:  * 42% of our senior management roles are held by women  * Our enhanced family leave policies * Launching our partnership with Code First Girls  * Increasing awareness of neurodiversity in the workplace through our partnership with the Inclusive Group  Our hiring process and what you can expect: Application: a member of our talent acquisition team will review your application against the key requirements for the role and let you know within two weeks whether you’re moving forward to the next stage;  Screening: You’ll spend 30-45 minutes speaking to one of our recruiters learning more about the role and ClearBank, and we’ll get it know more about you, your experience and how your skills align with the role (this will be via phone or Teams video call). You can expect to hear back from us within seven days following this meeting (if things are taking longer than expected, we’ll let you know that too);  First Interview: You’ll spend one hour with a member of our hiring team focusing on your skills, competencies and your ways of working at the same time we’ll give you time to ask more questions about the role, the team and learn more about the ClearBank culture. This will be via Teams.   Second Interview: This will be a competency-based interview with one or more members of our team. Final Stage: You will have a final meeting with the Head of Department. This will be around 45-60 minutes.   Offer: Congratulations! Get ready to transform banking forever!    Our commitment to you as a candidate:  We will always try our best to get back to you within seven days of your interview whether you’ve been successful or not and provide you with feedback. Sometimes things take a little longer, so we may not have a decision to share but we will get it touch to let you know we need a little more time.   We’re unable to provide specific individual feedback at the application or screening stage but know that your application was reviewed and considered carefully.   We wish you the best of luck with your application and maybe we’ll be celebrating your new role at ClearBank soon!   Equal Opportunities ClearBank is committed to ensuring equal opportunities throughout every stage of the recruitment process. ClearBank recognises that diversity is vital to the long-term success of the business in the communities and markets in which it operates. ClearBank is also a firm believer that an inclusive culture fosters greater employee engagement and collaboration.  ClearBank strives for diversity and inclusion of all forms, including (but not limited to): gender, age, educational and professional background, disability, gender reassignment, marital or civil partner status, pregnancy or maternity, race, colour, nationality, ethnic or national origin, religion or belief and sexual orientation.  As part of the Company’s commitment to equal employment opportunity, we provide reasonable adjustments, to candidates during the recruitment process, including to individuals with disabilities. We want to create a safe space that welcomes everyone so please let us know how we can accommodate you. In case you have any accessibility requirements you can share that with our Talent Acquisition team prior to your interview stage, if applicable.  The legal bit By submitting your CV to ClearBank Limited you are providing your consent for us to use the information you provide for recruitment purposes. For more information on how we manage your data go and check out our Candidate Privacy Notice on the ClearBank website to see how we process, manage and look after your data. You are also allowing us to communicate with you by email and telephone for recruitment purposes.

Sumup

About the team The Global Bank engineering organisation is responsible for the financial infrastructure that powers SumUp's banking products across multiple markets — and this role sits at the heart of it. As a Senior Engineering Manager, you'll provide leadership across a critical product area and cross-cutting initiatives, ensuring engineering delivery is resilient, scalable, and aligned with regulatory requirements. What makes this opportunity genuinely exciting is that you won't just be stepping into an existing structure — you'll be the first Senior EM based in London, with the mandate to build a team around you and grow a meaningful engineering presence in one of the world's strongest tech talent markets. 🤓Learn more about the Global Bank at SumUp What you'll do * Lead and develop a group of Engineering Managers, supporting their growth through coaching, skip-levels, and performance conversations, while also directly managing a small squad of engineers in London * Own one or more strategic engineering initiatives within the Global Bank — defining scope, aligning with product leadership, and driving delivery across squads and tribes * Establish and uplift tribe-wide engineering practices across areas such as observability, incident response, security, or AI workflows, setting standards that go beyond a single squad * Act as a senior escalation point for production incidents and complex cross-squad technical challenges, driving resolution and follow-through * Partner closely with InfoSec, Risk, Compliance, and Internal Audit to ensure engineering practices meet regulatory requirements and are audit-ready * Serve as a bar raiser in hiring panels and talent reviews, helping to maintain a consistent and high standard of engineering across the tribe You'll be great for this role if … * Proven track record of managing Engineering Managers, with experience in coaching, performance management, and talent reviews in a complex, multi-squad environment * Strong technical background in backend or full-stack engineering, with enough hands-on depth to earn credibility with engineers and contribute meaningfully to technical decisions * Experience owning cross-functional or cross-tribe initiatives that shaped technology direction at an organisational level * Ability to operate effectively in ambiguity, communicate clearly across technical and non-technical audiences, and guide teams through shifting priorities with confidence * Comfort navigating regulated environments — whether financial services, healthtech, or similar — where compliance and audit readiness are part of the day-to-day Why you should join SumUp * 🌎 Opportunity to work with a truly global, multicultural team from our central office location - this involves an office-first setup * 🌈 Commitment to Diversity and Inclusion: be part of a workplace that values and promotes diversity, fostering an inclusive environment where everyone's perspectives are respected and embraced * 🚀 Enrolment onto our Virtual Stock Option programme: you will own a stake in SumUp's future success * 🏖 Generous time off: enjoy 28 days of paid leave, plus bank holidays and special leaves * 📚 A dedicated annual L&D budget for attending conferences and/or advancing your career through further education * 🏥 Health matters: private health insurance, including optical and dental * 🚗 Life made easier: salary-sacrifice commuter benefits via Gogeta * 💼 Financial security: retirement scheme (SumUp matches 7% when you contribute 5%) * 🛡 Peace of mind: life insurance from MetLife for 2× your salary * 🌴 Break4me: 1-month sabbatical after 3 years of service * 🔗 Referral Bonus: earn additional rewards by referring talented individuals to join the SumUp team * 🌍 We support Visa sponsorship for this role About SumUp Be empowered to do more that matters. At SumUp, we're on a mission to empower small businesses across the globe by providing simple and affordable tools that allow them to thrive. Today, over 4 million businesses in 37 markets rely on SumUp as their financial partner to manage payments, finance and customer relationships. Our commitment to small businesses is reflected in our diverse team of over 3,000 SumUppers from over 90 nationalities, united by global collaboration and an innovative mindset. Our core values lay the foundation for who we are and what we stand for, shaping our work culture and driving our success. We foster inclusivity and a continuous learning culture, providing a safe space for personal and professional growth. Our differences make us unique and strong as we strive to create an environment where everyone belongs and feels supported, no matter how they identify. SumUp is proud to be an Equal Employment Opportunity employer, actively seeking and embracing diversity in our workforce. We don't make hiring or employment decisions based on race, colour, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender identity, sexual orientation, disability, age or any other basis protected by applicable laws or prohibited by company policy. Our commitment extends beyond recruitment to creating a safe and respectful workplace where harassment of any form is strictly prohibited. Discover more about our culture and opportunities on our careers website, and follow our journey on LinkedIn, Instagram, and TikTok. Job Application Tip We recognise that candidates feel they need to meet 100% of the job criteria in order to apply for a job. Please note that this is only a guide. If you don’t tick every box, it’s ok too because it means you have room to learn and develop your career at SumUp.