Clinical Expert, Onco-Immunology

Bioptimus

Bioptimus is building the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovation in biomedicine. With more than $75M in funding, Bioptimus is a fast-growing start-up headquartered in Paris, incorporated in October 2023. Backed by leading international venture capitalists, our world-class team of scientists and engineers is redefining the frontiers of AI and life sciences.  CLINICAL DATA MANAGER (SENIOR) Bioptimus’ mission is to accelerate biomedical innovation by building the reference foundation model of biology that will unlock AI superpowers for the biomedical ecosystem. As a well-funded and fast-growing start-up headquartered in Paris and incorporated in October 2023, we are growing a world-class team of scientists, engineers, and product leaders. This is a remote role. We’re headquartered in Paris, but the position can be performed remotely outside of Paris. ABOUT THE ROLE We are looking for a technical, execution-focused Clinical Data Manager to bridge the gap between unstructured, real-world data, and our frontier AI models. In this role, you will be the authority on clinical data structures, serving as the technical link during conversations with our global partners to standardise and harmonise data pipelines. Operating within our STELA program, you will structure our clinical datasets. You are a hands-on technical expert who writes reproducible code, enforces incoming data QC, and designs the data dictionaries and ontologies for our models. ABOUT THE STELA PROGRAM We recently launched the Spatial Tissue Embedding Learning Atlas (STELA)—a multinational spatial data generation initiative anchored by strategic partnerships with 10x Genomics and Broad Clinical Labs. STELA serves as the data backbone for M-Optimus, aiming to profile up to 100,000 patient specimens across three continents (US, Europe, and Asia). This will integrate high-resolution spatial transcriptomics, histopathology imaging, and longitudinal clinical records to bring forward the next era of biological AI and precision medicine. WHAT YOU'LL BE DOING ---------------------------------------------------------------------------------------------------------------------------------- As our Clinical Data Manager, you will operate at the intersection of data engineering, clinical science, and partner collaboration across two strategic domains: PARTNER DATA ENGINEERING & COLLABORATION * Technical Partner Interface: Participate directly in technical conversations with external partners (hospitals, research institutions, CROs/CMOs). Dive into the details of diverse clinical data structures to understand how data is captured, stored, and extracted. * Order from Uncertainty: Translate ambiguous source data into harmonized, AI-ready assets. * Ontology Integration: Map and align diverse clinical data to industry-standard biomedical ontologies (e.g., SNOMED, ICD, etc…) with an emphasis on clinical oncology and immunology data. DATA GOVERNANCE, QUALITY, AND AUTOMATION * Data Dictionary Architecture: Design, build, and maintain data dictionaries, schemas, and metadata models that align with STELA’s multimodal pipeline requirements, while ensuring integration with existing pipelines. * Enforcing Ingest Quality: Establish, automate, and enforce data quality control (QC) and validation frameworks to check incoming partner data for integrity, completeness, and programmatic consistency. * Reproducible Pipeline Code: Write production-grade Python code to automate data cleaning and harmonization tasks. CLINICAL REALITY & INTUITION * Clinical Reality: Practical understanding of how clinical data is generated in the real world (hospitals, trials, CROs). You understand the gaps between ideal protocols and messy clinical realities, and you know what red flags to look for in incoming data. * The Investigative Mindset: You know what questions to ask partners to get to the "ground truth" of their data structures. Actively audit data to find missing variables, anomalies, and hidden biases. * Oncology/Immunology Domain Knowledge: Familiarity with cancer progression metrics (e.g., RECIST criteria, TNM staging, longitudinal treatment lines like immunotherapy vs. chemotherapy) so you can recognize what data is important.   WHAT YOU'LL BRING ---------------------------------------------------------------------------------------------------------------------------------- The successful candidate will have a ‘team-first’ attitude; be independent, curious, and detail-oriented; thrive in a dynamic, fast-paced environment; and be fun to work with. You possess the rare ability to confidently lead complex technical alignment meetings with partners while simultaneously being excited to roll up your sleeves and write code. TECHNICAL & PROFESSIONAL QUALIFICATIONS * Educational Background: Bachelor’s or Master’s degree in Life Sciences, Bioinformatics, Health Informatics, Computer Science, Statistics, or a related quantitative field. Equivalent practical industry experience is highly valued. * Industry Experience: A few years (typically 3–5+) of hands-on experience in clinical data management or clinical data engineering within a CRO, CMO, pharma, or biotech environment. Proven track record of taking messy partner data and building reproducible, production-grade workflows. * Hands-on Coding Skills: High proficiency in Python and standard data science libraries (e.g., Pandas, NumPy) for data manipulation, cleaning, and validation. * Software Best Practices: Demonstrated commitment to code reproducibility, including strong experience with Git version control and building reusable data pipelines. * Clinical Data Expertise: Familiarity with clinical data structures, electronic health records (EHR), case report forms (CRFs), and longitudinal clinical trial data. * Ontologies & Vocabularies: Knowledge of standard clinical and biological ontologies, specifically those tailored to cancer/oncology and/or immunology datasets. PARTNERSHIP & EXECUTION SKILLS * Communication & Alignment: Ability to align on data delivery formats with a partner clinical teams. * Start-up experience: Comfort working in a fast-paced startup environment where data schemas evolve and ingest requirements must be defined from scratch.   HOW TO STAND OUT ----------------------------------------------------------------------------------------------------------------------------------   * Experience with cloud computing platforms (AWS, GCP, etc…) * Experience working directly with multimodal datasets (e.g., matching clinical records with omics or digital pathology imaging). * Understanding of CDISC standards (SDTM/ADaM) combined with a modern tech-stack approach (beyond legacy SAS programming). * Experience building or optimizing ETL pipelines for large-scale biobanks or multinational clinical consortia.   THE CANDIDATE JOURNEY ---------------------------------------------------------------------------------------------------------------------------------- To be considered, please submit your CV in English. We believe in a transparent and collaborative interview process. Here is what you can expect after submitting your application:   * Screening: A 30-minute introductory call with the Hiring Manager to discuss your background, motivations, and the position in more detail. * Interviews: Following a successful screening, you will be invited to a series of interviews: 1. Data Strategy Panel Presentation (45 min): You will present a short overview of a past data management challenge you overcame (e.g., designing a complex data dictionary or aligning messy CRO data), followed by Q&A. 2. Technical Deep Dive (30 min) - There will be 1 additional break out session to do a deep dive with 1-2 Bioptimus Engineers 3. Executive Interview (30 min): A discussion with member(s) of our Senior Leadership focusing on long-term vision, cultural fit, and mutual potential. * Offer: Following the completion of all interviews, our hiring team will make a final decision. Please note that an offer is contingent upon the successful completion of a reference check. * Onboarding: Welcome to the team! We will begin your onboarding to get you fully integrated at Bioptimus!   WHY THIS IS A UNIQUE OPPORTUNITY ----------------------------------------------------------------------------------------------------------------------------------   * Join a mission-driven team redefining biology through AI. * Work in a collaborative, high-autonomy, high-impact environment. * Contribute to pioneering research, infrastructure, or strategy at the ground floor. * Competitive compensation, equity, and flexibility (remote options). * Help shape the scientific and technical culture of a category-defining company. ----------------------------------------------------------------------------------------------------------------------------------   We believe that the unique contributions of all Bioptimists create our success. To ensure that our culture continues to incorporate everyone’s perspectives and experience, we never discriminate based on race, religion, national origin, gender identity or expression, sexual orientation, age, or marital, or disability status. Decisions related to hiring are made fairly, and we provide equal employment opportunities to all qualified candidates. We take responsibility for always striving to create an inclusive environment that makes every employee and candidate feel welcome.

Avelios Medical

ABOUT US Our mission at Avelios is to unlock clinical data to power seamless healthcare operations for better patient care. To do so, we have built a modular software platform that digitizes and optimizes workflows in hospitals with cutting-edge technology in a user-friendly way. With our software, we enable hospitals, doctors & nurses to provide their patients with the best possible care. We are growing fast and want to keep expanding our team and business to fundamentally digitize healthcare for the better. We appreciate different backgrounds and see diversity as one of our strengths. THE TEAM AND ROLE As a Medical Consultant (all genders), you will take responsibility for shaping the clinical and process-related foundation of customer projects after contract closure. Acting as a key clinical expert within the Project team, you work closely with hospital stakeholders and internal teams during the project implementation phase to enable successful go-lives. YOUR RESPONSIBILITIES * Managing key stakeholders across customers, the Project team, and the Product team throughout the configuration phase * Leading clinical process and requirements workshops with hospital stakeholders during the configuration phase, including software demos * Representing and consistently applying the Avelios best-practice standard across existing modules * Aligning clinical target processes with customers and defining clear go-live and rollout scopes * Identifying needs for product adjustments and coordinating closely with the Product team to enable scalable improvements YOUR QUALIFICATIONS * Several years of professional experience in hospitals (e.g. physicians, doctors, nursing, functional departments, controlling) or extensive consulting experience in hospital transformation or IT projects * Strong understanding of hospital workflows and the ability to structure and analyze complex clinical and operational requirements * Excellent communication skills, including confident customer communication, the ability to moderate workshops, explain complex topics clearly, and handle conflicts in a professional and empathetic manner * Experience in hospital digitalization projects, including working with hospital information systems (KIS) and translating clinical requirements into structured artifacts (e.g. workflows, use cases, requirements), is a plus. * Fluency in German and English (spoken and written) YOUR BENEFITS * A promising opportunity to establish a Medical Consulting Team in a scale-up backed by leading international VCs, SAP and Fresenius * An international, informal team structure in a motivating scale-up atmosphere, allowing you to participate directly in our growth story and the overall success of Avelios * A virtual stock option package (VSOP) that lets you benefit from Avelios’ long-term value creation * A monthly meal allowance of up to 75 euros, full coverage of the Deutschlandticket, Urban Sports Club or a subsidized Wellpass membership, a bike leasing program and Corporate Benefits that give you access to discounts from a wide range of providers in various

Scarlet

We pull medical technology from the future to solve human health.   Authorised by governments around the world to assess medical AI, we remove unnecessary delays from every regulatory approval we do so patients get devices from the future, today. We are proud to count the world’s most ambitious companies building medical technology as customers. You will be joining a team with product-market fit, flowing data, and exponentially growing revenue. About this role: We are creating a network of clinical specialists who can provide targeted clinical insight on medical devices during regulatory assessments. This is not a full-time role. Instead, specialists join a roster and are contacted when their clinical expertise is relevant to a specific device or assessment question. Typical engagements are short (e.g., a few hours of review or discussion) and occur on an as-needed basis. Your input helps ensure that certified devices demonstrate appropriate clinical performance, safety, and benefit for their intended clinical use. Key Skills: Education - A degree in clinical medicine, nursing, dentistry Certification - Certified specialisation in a medical field Registration - Current registration as a medical practitioner