Principal Product Data Scientist

Isomorphic Labs

Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery.  Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you.    ABOUT ISO Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI.   Your Impact We are building the largest foundation models in biotech and applying them immediately to cure disease. You will play a pivotal role in ensuring the reliability and scalability of the foundations that make this possible. As a Principal Engineer, you will lead the efforts to harden our systems, ensuring our groundbreaking AI is built on an unshakeable base, working closely with the research team and the Applied ML teams to ensure the infrastructure is stable, reliable and can operate with more data and larger models as we grow.  What You Will Do * Develop and operate our inference platform, serving fleets of cutting-edge machine learning models to scientific applications. * Design strategy and build roadmaps for maturing the platform. * Architect and optimize our next-generation inference services. You will solve core scaling limits, ensuring high-throughput performance and feature parity across our model serving stack. * Contribute to core technical decisions on tooling and architectural design while partnering with science, product, and operations teams to align infrastructure with biotech R&D cycles. * Deliver high-quality and well-tested user-focused features. Skills and Qualifications Essential: * Proven experience in architecting and managing large-scale AI/ML workloads in a production environment. * Expertise in cloud compute design, specifically within Google Cloud Platform (GCP). * Orchestration: Significant experience deploying and managing complex workloads within Kubernetes (GKE). * Professional familiarity with NVIDIA GPU generations and the intricacies of high-performance compute. * Strong programming skills and a "reliability-first" approach to software development. Nice to Have: * A career history that spans both ML Software Engineering and Infrastructure SRE roles. * Experience leading multi-disciplinary projects and navigating complex stakeholder requirements in a fast-paced environment. * Familiarity with workload scheduling, ML efficiency research, and hardware benchmarking. * Experience with Google TPU generations and specialized ML-driven R&D cycles. CULTURE AND VALUES We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.  Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. CREATING AN EXTRAORDINARY COMPANY We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. HYBRID WORKING It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our privacy policy. >> Click to view other open roles at Isomorphic Labs

ClearScore

Principal Product Manager – Upstream (Mortgages) At ClearScore we’re on a mission to help people achieve greater financial wellbeing. Within our Upstream mission, we focus on shaping and scaling new propositions that unlock meaningful value for our users. A pathway to homeownership is a key milestone in our users’ journey to financial wellbeing. We’re expanding our product team to support our global strategy in homeownership and mortgages. As a Principal Product Manager working in our newly formed Upstream Mortgages team, you will hold responsibility for the viability and roadmap direction of this emerging vertical within the ClearScore ecosystem. Reporting into the VP, Global Product, you will be central to shaping our Mortgages vertical — building on strong early foundations while evolving and extending the proposition from first principles where needed. You will define roadmap content and sequencing, make clear trade-offs across user experience, commercial opportunity and build complexity, and ensure the proposition delivers sustainable value to our users and partners. You’ll operate within a shared leadership model alongside a senior Design Lead, jointly guiding a cross-functional team spanning Product, Design, Engineering and Data. While you will not have direct line management responsibility, you will play a central role in setting priorities, structuring work and driving clarity of decision-making across the team. This is a high-impact role at the centre of bringing a complex new vertical to market, shaping how ClearScore shows up in one of the most important moments in our users’ financial lives. It requires strong product judgement, commercial awareness and the confidence to make well-reasoned decisions in a multi-stakeholder environment. What you will be doing: * Build on existing strategic thinking, identifying clear paths to user, partner and business value and shaping the proposition’s continued evolution. * Develop and maintain deep expertise in the homeownership and mortgages landscape, building strong external awareness across partners, regulation and industry trends to inform product direction. * Own the global roadmap for the homeownership and mortgages proposition, defining priorities and sequencing to ensure long-term viability and coherence in line with overall strategy. * Lead structured product discovery to validate desirability, viability and feasibility, using qualitative insight, quantitative data and commercial understanding to inform decisions. * Make clear, balanced trade-offs between user experience, commercial constraints and technical complexity, ensuring focused and coherent progress. * Partner closely with Design to deliver a compelling, simple and user-centred experience within a complex domain. * Collaborate with Commercial and Data stakeholders to ensure the proposition is grounded in market dynamics, partner realities and measurable outcomes, while retaining clear accountability for product direction. * Structure ambiguous problem spaces into clear work-streams, guiding and elevating work across the team — including elevating the quality of thinking and execution across more junior Product colleagues. * Drive momentum and decision-making, ensuring stakeholders are meaningfully engaged throughout the innovation lifecycle.   Skills we'd love you to have * You know what good Product Management looks like and are comfortable owning meaningful proposition-level problem spaces within an established strategic direction. * You have demonstrated experience shaping new propositions from first principles, not only optimising existing products. * You are confident shaping roadmap direction and making clear trade-offs across competing constraints. * You are commercially aware and think in terms of value exchange, incentives and long-term proposition coherence — not just feature delivery. * You are comfortable operating within a shared leadership model, partnering closely with senior Design while retaining clear accountability for product viability. * You bring clarity to complex discussions and are able to move from alignment to decision — making well-reasoned calls even when consensus is incomplete. * You are intellectually confident and willing to challenge existing thinking constructively where evidence or judgement suggests a better path. * You combine structured discovery with strong product intuition, balancing rigour with momentum and knowing the fastest routes to validate key hypotheses. * Experience in mortgages or adjacent regulated financial products is highly desirable, though strong product craft and ClearScore ecosystem understanding may compensate.   Why ClearScore? ClearScore is the UK's #1 credit score and report app. We are also present in South Africa, Australia and Canada, with more than 20 million users globally and growing fast. Someone joins ClearScore every 20 seconds. We have established relationships with over 50 of the main lenders in the U.K., and have been a trusted tool for customers to manage their credit and make better financial decisions. Since October 2016 we have helped 1.8 million users take out a new credit card or loan. We are user-centric at our core and we believe in leveraging technology to enable positive financial choices. We are design-led and data-driven and we embed these behaviours in everything we do. Our company culture is a fundamental part of all we have achieved. We believe in hiring smart, driven, passionate and diverse people who are keen on having a real impact in our organisation. We trust you to manage your own time so we offer flexible work and no fixed desk hours. We don't micromanage and we believe in measuring outcomes rather than effort. We have an inclusive culture where all, regardless of seniority, are encouraged to contribute with their ideas, look after their wellbeing and actively seek opportunities for career growth. If you feel like this could be the place for you, apply and our Talent team will be happy to share more. Benefits: * 25 paid holidays and a “duvet day” on your birthday * Hybrid Work Environment * Private health and dental cover - including mental health support through Bupa  * GP office visits * Life assurance scheme * Up to 6% matched pension * Regular Lunch and Learns with guest speakers * Dog-friendly office * Daily breakfast and free snacks * Access to discounts via Cobens Extras  * Free sports and social clubs * Continued investment into learning and development  * Leadership-led training * In-house psychotherapist * Financial coach to help you plan and achieve your goals * No clock-watching culture * Generous maternity and paternity plans * Culture and inclusion representatives * Transparent pay structure and a career growth plan   Equal Opportunities ClearScore is committed to providing equal employment opportunities to all qualified individuals. As an equal opportunity employer, we are able to make reasonable adjustments to accommodate individuals with disabilities during the recruitment and selection process. If you require accommodation, please inform us in advance, and we will work with you to meet your needs. Our Hybrid Model   We embrace a dynamic hybrid work environment that balances flexibility with collaborative in-person experiences. Our approach is designed to foster innovation, team connection, and individual productivity. * Levels 1-5: Minimum 2 days per week in-office * Level 6 and above: Minimum 3 days per week in-office We believe this structure offers the best of both worlds - the flexibility of remote work and the synergy of face-to-face collaboration. Our office days are carefully coordinated to maximise team interactions and learning/ mentorship opportunities. What This Means for You: * Flexibility to manage your work and life * Dedicated in-office days for team building and collaborative projects *  Office facilities (with plants!) designed for productive interactions * Clear expectations and support for maintaining our hybrid schedule We’re committed to creating an inclusive environment that accommodates diverse needs while maintaining our collaborative culture. Join us in shaping the future of work! Note: While we offer flexibility, commitment to our hybrid schedule is an important aspect of our team culture and performance expectations.     Inclusion Policy We are always looking for talented individuals to join ClearScore. We are an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for our people. Please see our People Policy Notice at https://www.clearscore.com/people-notice.

Skyscanner

About Skyscanner Everyone loves travelling, but planning is not without its challenges ✈️. That's why we've spent 20 years building tools that turn travel-planning chaos into a breeze. Today, around 160 million travellers count on us every month to skip the whole “47 browser tabs open” phase and find flights, cars, and hotels quickly and easily 💻. Joining Skyscanner means becoming part of a global brand that's striving to become the planet's go-to travel hack accessible for all 🌍. Our vision? To be the world's number one travel ally. (Ambitious? 💪 Yes, but, hey, that's what got us here) Now, we’re on the lookout for an Principal Product Manager - Loyalty to help us bring that vision to even more travellers.    About the role (Hybrid) We’re looking for a product lead to join our loyalty team. At Skyscanner, we’re on a mission to help every traveller to explore our world effortlessly. As we continue to grow the audience we serve, it’s critical that we build relationships with our travellers that create reasons to return directly, time and time again. We’re looking for an experienced product manager to help shape, define and deliver our loyalty strategy, with an ambition to greatly increase our direct relationships, drive retention and increase customer lifetime value. Through our loyalty programme we’re aiming to offer better prices to our most loyal travellers, help them move from searching to trip planning, offer them reoccurring rewards at the airport, and broadly better personalising their experience throughout. In this role you’ll need to manage stakeholders across the organisation to drive substantial change. What you’ll be doing * Partnering across the business: You’ll work with cross-functional teams on complex initiatives spanning proposition execution, experience design, experimentation and platform delivery — from marketing and design to data, engineering and legal. * Translating vision into product: You’ll turn loyalty proposition and experience principles into concrete capabilities, journeys and interactions across web, app, SEO, booking flows and lifecycle touchpoints. * Owning the roadmap: You’ll define and execute a phased loyalty product strategy — shaping MVPs, proofs of concept and iterative releases that balance learning, impact and technical foundations. * Spotting the biggest opportunities: You’ll collaborate with squads and stakeholders to identify gaps and unlock initiatives that drive engagement, retention and long-term traveller value. * Coordinating end-to-end delivery: You’ll ensure smooth execution across Flights, Hotels, Cars, Packages, Explore, Platform, Data and Lifecycle systems — no dropped handovers, no mystery dependencies. * Making smart product decisions: You’ll define feature-level requirements and make day-to-day product and UX calls that keep experiences intuitive without compromising core conversion flows. * Leading experimentation: You’ll define hypotheses, success metrics and guardrails, run experiments and use the learnings to continuously refine the roadmap and loyalty proposition. About you * Loyalty-savvy: You’ve designed, built or scaled loyalty programmes or retention-led experiences, and you deeply understand how rewards, recognition and lifecycle touchpoints shape behaviour. * Influential product leader: You’re comfortable aligning diverse stakeholders around complex, cross-cutting initiatives - bringing clarity where others see chaos. * Data-informed decision maker: You’ve hands-on experience with experimentation, metrics and guardrails, with a strong focus on long-term value, repeat behaviour and retention. * Platform confident: You’re comfortable navigating complex environments, balancing short-term wins with long-term capability building and dependency management. * Outcome-oriented: You thrive in fast-paced, ambiguous settings and focus on impact over optics. * Clear communicator: You bring excellent collaboration skills and experience working in agile environments, keeping teams aligned and energised. * Traveller-first thinker: You instinctively zoom out to see the whole journey — always asking how this makes life easier, better or more rewarding for the traveller. #LI-SM2 #LI-Hybrid What it's like here We are the real deal - no corporate gloss, no empty promises. Just a team of genuinely curious, caring humans ❤️, building things that help travellers explore the world a little easier 🧭. Skyscanner is made up of brilliant humans from every corner of the world. We believe travel makes the world better - and that the same is true of our diverse teams. We're proud to be an equal opportunities employer and are committed to building an inclusive workplace where everyone can thrive and products that are accessible to all ✨. Sound like your kind of adventure? 🚀 Apply now and help us shape the future of travel. We're committed to ensuring our application and recruitment processes are inclusive and accessible to everyone. If you require any reasonable adjustments or accommodations for interviews, and/or wish to apply under the Disability Confident scheme, please let your recruiter know. If you’d like more information on any of our policies, such as hybrid working or Parental Leave policies (typically we pay a minimum of 24 weeks birth parent/maternity leave globally), our recruitment team can provide more information on these. #LI-EM2