Search results for "Metabolic Health"

Vill du arbeta i en engagerad och utvecklingsinriktad dietistverksamhet med stark kollegial gemenskap? Hos dietistmottagning primärvård i Region Värmland får du en varierad vardag med nära samarbete, goda utvecklingsmöjligheter och fokus på kvalitet, evidens och patientnytta. Din arbetsplats Dietistmottagning primärvård är en del av Hälsa och rehabilitering i Region Värmland. Vi tar främst emot remisser från länets vårdcentraler, och sitter fysiskt på några av dessa. Vår mottagning består av 11 dietister och två vårdadministratörer samt vår enhetschef. Utöver dietistmottagningens täta samarbete och kollegor får du också en självklar plats i arbetsgruppen på Kristinehamns vårdcentral, där du har din fysiska arbetsplats. Förutom arbetet med vårdcentralernas patientgrupper har vi flera spännande samarbeten med andra enheter inom regionen. Tillsammans med mödravården arbetar samtliga dietister med LEVA-metoden. Enskilda dietister arbetar med måltidsprojekt inom Rättspsykiatrin och på våra närvårdsavdelningar (NÄVA) i Säffle och Kristinehamn. Att ha olika förgreningar utifrån vårt grunduppdrag uppmuntras och skapar möjligheter till karriärutveckling, berikar vår arbetsplats med nya perspektiv och ger ytterligare variation i arbetet. Genom våra utvecklingsgrupper, som är diagnos- och ämnesuppdelade, har du som medarbetare stor påverkansmöjlighet för hur vi framåt ska möta patienternas behov genom tillgänglighet och kloka kliniska val. Vår enhet präglas av engagemang och en aktiv dialog - hos oss har du alltid nära till en yrkeskollega! Som arbetsgivare vill vi ge dig möjlighet att utvecklas och trivas hos oss, därför satsar vi på din arbetsmiljö och dina möjligheter att skapa en spännande karriär och tillvaro hos oss. Dina arbetsuppgifter Som dietist på dietistmottagning primärvård jobbar du med enskild nutritionsbehandling enligt Nutritional Care Process (NCP) med vuxna 18 år och uppåt. Vanliga diagnoser som vi möter är malnutrition, diabetes typ 2, IBS och obesitas. Vi erbjuder också LEVA-metoden, en viktminskningsmetod för kvinnor postpartum. Behandlingen har ett specifikt upplägg där fysiska besök blandas med tät digital kontakt i Stöd- och Behandlingsplattformen. Du har frihet att lägga upp en egen struktur i tidboken för din arbetsdag och variera mellan fysiska besök, digitala besök och gruppbesök. Vi prioriterar det fysiska mötet med både patient och andra kollegor men möjlighet finns till 20 procent distansarbete. Dina kunskaper och kompetenser Du är legitimerad dietist med ett stort engagemang för att hjälpa människor till ett hälsosammare liv, med hjälp av nutritionsbehandling. Du har vetenskap och evidens i fokus och ser positivt på möjligheter till nya samarbeten och arbetssätt. Du har förmågan att se helheter, tar hänsyn till det större perspektivet och ser till hela verksamhetens bästa i agerande och beslut. Som person är du stabil och trygg i dig själv, samtidigt som du strukturerar och organiserar ditt arbete på ett effektivt sätt. Du bygger goda relationer och kan arbeta självständigt när det behövs. Om detta låter som du, kan du bli en del av vårt team! Vi befinner oss just nu i semesterperioden, vilket innebär att handläggningstiden kan vara något längre än vanligt. Rekryteringsarbetet återupptas efter semestrarna och vi återkopplar så snart vi har möjlighet. Tack för ditt tålamod! Om Region Värmland Vi är till för att alla som bor här ska må bra och för att vår region ska vara attraktiv och konkurrenskraftig. Vi gör skillnad inom hälso- och sjukvård, tandvård, kollektivtrafik, regional utveckling och kultur och bildning. Vi möter människor i livets största stunder och i alla de där vardagsögonblicken där emellan. Vår vision är livskvalitet i världsklass. Läs mer om hur det är att jobba hos oss och våra förmåner och följ oss på sociala medier.  Vill du också jobba för alla i Värmland? Välkommen med din ansökan.  Övrigt Från 7 juni 2026 gäller EU:s lönetransparensdirektiv - för ökad öppenhet och rättvisa löner. Information om kollektivavtal finns på SKR:s webbplats, Kollektivavtal -SKR I samband med eventuell anställning kan vi komma att be dig som sökande att lämna ett utdrag ur polisens belastningsregister. Inför anställning inom psykiatrisk vård, vård av funktionshindrade, vård av barn eller ungdomar gör arbetsgivaren en kontroll i polisens misstanke och belastningsregister. Ett utslag i detta register kan komma att påverka din möjlighet till anställning. Har du skyddad identitet och vill göra en ansökan ber vi dig att kontakta Kompetensförsörjningsenhet HR via Regionens växel 010-831 50 00. Då får du hjälp att lämna in din ansökan utan att den hanteras i Varbi. Tänk på att endast ta med information som är relevant för den aktuella befattningen. Inför rekryteringsarbetet har Region Värmland tagit ställning till rekryteringskanaler och marknadsföring. Vi undanber oss därför alla erbjudanden om annonserings- och rekryteringshjälp i samband med denna annons.

Do you want to contribute to top quality medical research? We invite applications for a Research Assistant position in the research group of Professor Magnus Ingelman-Sundberg, within the Section of Pharmacogenetics.   This position is housed in the Department of Physiology and Pharmacology, known for its collegial, international, and dynamic research environment. Our current research focuses on the use CYP2C19 is a highly polymorphic enzyme involved in the metabolism of many drugs and endogenous lipids, making it one of the most clinically important pharmacogenes. Beyond drug metabolism, CYP2C19 regulates lipid pathways influencing vascular function, inflammation, cholesterol homeostasis, and broader metabolic processes. We will investigate why fetal CYP2C19 expression induces inflammation in the developing hippocampus, leading to neuronal degeneration in the adult dentate gyrus causing anxiety and depression in adult life identifying molecular pathways relevant for future antidepressant development. Reduced CYP2C19 function has been associated with increased risk of myocardial infarction and ischemic stroke, suggesting broader roles in cardiovascular disease. Using advanced human liver spheroids and brain organoids, we will study CYP2C19 in lipid metabolism ini relation to cardiovascular risk, by identifying CYP2C19-dependent lipid pathways providing new insights into mechanisms underlying neuropsychiatric disorders and arteriosclerosis.   Your profile We are seeking a motivated candidate with at least one year of hands-on laboratory experience and practical skills in RT-PCR, Western blotting, and cell culture. Experience in immunohistochemistry, imaging techniques, and molecular biology methods is highly desirable. Previous work with brain tissues is a merit. You will join a dynamic research team of approximately six researchers and contribute to several ongoing projects focused on the biological functions of CYP2C19. Your primary responsibilities will include: · Analysis of lipids regulated by CYP2C19 using advanced 3D human liver spheroids as an experimental model. · Characterization of developmental alterations in the fetal brain caused by CYP2C19 overexpression using approaches such as immunohistochemistry, RNA sequencing, and ELISA. · Development and use of in vitro macrophage activation systems to investigate whether CYP2C19-dependent lipid mediators promote inflammatory pathways relevant to atherosclerosis and cardiovascular disease. While knowledge of the Swedish language is advantageous, fluency in both oral and written English is essential. The successful candidate will be a team player with excellent communication skills, well-organized, and enjoy interacting with researchers and students.   What We Offer Karolinska Institutet is one of the world's leading medical universities. Our vision is to advance knowledge about life and promote better health for all. At Karolinska Institutet, we conduct successful medical research and offer the largest range of medical education in Sweden. As a state university, we provide numerous benefits through our collective agreement, including access to modern wellness facilities with trained staff on-site. Location: Solna, Biomedicum MIS-lab : https://ki.se/en/people/magnus-ingelman-sundberg#about-me We look forward to your application!   The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form. Want to make a difference? Join us and contribute to better health for all Type of employment: Temporary position, 1 year Contract type: Full time First day of employment: According to agreement Salary: Monthly salary City: Stockholm Country: Sweden Contact: Magnus Ingelman-Sundberg, magnus.ingelman-sundberg@ki.se

PolyPeptide is on a transformative growth journey – expanding globally, investing in new technologies, and increasing our production capacity through major site expansions and strategic projects. As part of this, we are launching a global SAP S/4HANA implementation and building a new ERP function from the ground up. This is a rare opportunity to join from the beginning and contribute to the implementation and long-term support of a modern, scalable ERP system. We are now looking for an SAP Solution Specialist to join our Global IS/IT organization and play a central role in supporting the SAP platform’s reliability, integration, and compliance – from implementation through stabilization and future enhancements. About us PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide- and oligonucleotide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from pre-clinical through to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with a large exposure to metabolic diseases, including GLP-1. Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange. Our Values Trust: We build and maintain trust in all our relationships – both with each other and with our customers. We support each other and work as a team. Innovation: We are curious and driven by finding smart solutions to the challenges we face. Excellence: We always strive to deliver high quality and adapt to meet the needs of our customers. About the Role As the SAP Solution Specialist, you’ll be a vital part of our ERP team - bridging business functions, internal experts, and external partners. You will work closely with ERP Solution Managers and the ERP Solution Architect to support technical needs across the ERP landscape. This is a collaborative and technically focused role where you’ll combine deep SAP platform knowledge with the ability to troubleshoot, optimize, and contribute to the continuous improvement of our new global SAP S/4HANA environment – particularly across output management, integrations, platform reliability, and compliance. You’ll also play a key role in ensuring operational continuity and supporting validation, change control, and documentation activities during and after the ERP implementation. Key Responsibilities * Provide technical support and advanced troubleshooting within SAP S/4HANA, including integrations, output management, batch jobs, and custom developments. * Act as key technical partner to ERP Solution Managers across modules (Finance, Sales, Supply Chain, Manufacturing, etc.). * Oversee system performance and platform reliability – from day-to-day support to long-term improvements. * Take ownership of output management (e.g., SAP Output Management, NiceLabel) – including user requirements, documentation, testing, and deployment. * Coordinate with infrastructure and print teams on cross-functional technical deliverables. * Support validation, qualification, and compliance processes (e.g. GxP, 21 CFR Part 11, EU Annex 11). * Participate in CAB meetings, change control, and ticket resolution (incidents, problems, service requests). * Manage documentation for technical specifications, functional descriptions, SOPs, and user training. * Monitor license usage, system maintenance, and vendor coordination. * Support roadmap development, lifecycle planning, and communication of system changes to key stakeholders. Your Profile We are looking for a technically strong and business-oriented specialist who thrives in a dynamic and regulated environment: * A Master’s degree in Computer Science, Information Systems, Engineering, or a related field. * 5+ years of experience in SAP, including at least 3 years working with SAP S/4HANA platform and technical solution support. * Experience with E2E Output Management and SAP integrations. * Experience from the pharma/CDMO industry is an advantage. * Good understanding of ERP-related compliance requirements (GxP, validation, documentation, change control). * Strong communication and stakeholder management skills. * Proactive and collaborative mindset – with attention to detail and continuous improvement * Proficient in English, both speaking and writing. FIND THIS INTERESTING? APPLY NOW! Are you ready to take the next step in your career? The position will be open until August 31th, but we are applying an ongoing selection, so do not hesitate to send us your application. Due to summer vacation we will start going through the applications later in August. For more information, please contact Henrik Werdelin at henrik.werdelin@polypeptide.com. You are welcome to contact the local union chairman for Akademikerföreningen or Unionen at +46 040-36 62 00 for support.

PolyPeptide is on a transformative growth journey – expanding globally, investing in new technologies, and increasing our production capacity through major site expansions and strategic projects. As part of this journey, we are launching a global SAP S/4HANA implementation and building a new ERP function from the ground up. We’re looking for an experienced IS/IT Compliance & Validation Specialist to help ensure that our new enterprise systems – especially the ERP platform – are implemented and maintained in line with industry standards, regulatory requirements, and best practices. This is a unique opportunity to join in the ERP journey and take a central role in securing validation of a modern, global ERP system in close collaboration with Global QA. About us PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide- and oligonucleotide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from pre-clinical through to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with a large exposure to metabolic diseases, including GLP-1. Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange. United by Purpose At PolyPeptide, we take pride in contributing to medicines that make a real difference to people's lives and health. Here, you will become part of work that truly matters, every single day. We are driven by our core values: trust, innovation and excellence. This is reflected in how we collaborate, solve problems, and uphold our responsibility for quality and safety for the patients ultimately affected by our work. We are a company undergoing rapid development. Our growth brings a fast-paced environment, change and new opportunities for both employees and the business. Here, you will grow together with us. If you are looking for a workplace where purpose, community and development go hand in hand, then PolyPeptide is the right place for you. About the Role In this role, you will be part of our global IS/IT organization and act as a key resource in securing regulatory compliance across enterprise systems – with a primary focus on the new ERP program. You’ll be responsible for system validation (CSV), audit readiness, change control, and risk management, with a strong emphasis on maintaining compliance with GxP, 21 CFR Part 11, EU Annex 11, and GAMP 5. You will work closely with Global QA, IT, regulatory affairs, and external vendors to ensure that the new ERP platform and other digital systems are inspection-ready, properly documented, and aligned with pharmaceutical regulations and expectations. Key Responsibilities * Develop and execute validation strategies for GxP-relevant systems in accordance with GAMP 5 and biotech/pharma industry standards. * Author and review validation documentation such as validation plans, IQ/OQ/PQ protocols, traceability matrices, and summary reports. * Ensure systems comply with electronic records and signature regulations (21 CFR Part 11, Annex 11). * Perform risk assessments for new systems, upgrades, and system changes, and integrate validation into the change management process. * Maintain audit-ready documentation and support both internal and external audits, including regulatory inspections. * Address audit findings and contribute to corrective and preventive actions (CAPAs). * Collaborate with QA, regulatory, manufacturing, and IT stakeholders as well as external vendors to align on compliance and validation requirements. * Provide training and guidance on validation procedures, regulatory expectations, and documentation standards. Your Profile We are looking for a structured and proactive specialist who thrives in a regulated environment and enjoys collaborating across functions. You bring: * A Bachelor’s or Master’s degree in Life Sciences, Engineering, Computer Science, or similar. * 5+ years of experience in IT compliance, system validation, or QA in biotech, pharma, or another regulated industry. * Solid knowledge of GxP, GAMP 5, 21 CFR Part 11, and EU Annex 11. * Experience with computerized system validation (CSV) and quality documentation. * Familiarity with enterprise platforms like ERP, MES, LIMS, or QMS. * Excellent analytical, documentation, and communication skills. * Full professional proficiency in English. As a person, you are detail-oriented and accountable – and you take pride in building systems and documentation that stand up to inspection and support safe, efficient operations. FIND THIS INTERESTING? APPLY NOW! Are you ready to take the next step in your career? The position will be open until August 31 but we are applying ongoing selection so do not hesitate to send us your application. Due to summer vacation we will start going through the applications later in August. For more information, please contact Krister Svärd at krister.svard@polypeptide.com. Swedish applicants are welcome to contact the local union chairman for Akademikerföreningen or Unionen at +46 040-36 62 00 for support.

PolyPeptide is on a transformative growth journey – expanding globally, investing in new technologies, and increasing our production capacity through major site expansions and strategic projects. As part of this journey, we are launching a global SAP S/4HANA implementation and building a new ERP organization from the ground up. We’re now looking for an experienced SAP Test & Release Manager to take a central role in securing system quality, control, and compliance throughout the testing lifecycle and release process – with a primary focus on our new global ERP platform. This is a unique opportunity to join a global ERP transformation and help establish structured, reliable, and validated release and test processes that will support our operations for years to come. About us PolyPeptide Group AG and its consolidated subsidiaries (“PolyPeptide”) is a specialized Contract Development & Manufacturing Organization (CDMO) for peptide- and oligonucleotide-based active pharmaceutical ingredients. By supporting its customers mainly in pharma and biotech, it contributes to the health of millions of patients across the world. PolyPeptide serves a fast-growing market, offering products and services from pre-clinical through to commercial stages. Its broad portfolio reflects the opportunities in drug therapies across areas and with a large exposure to metabolic diseases, including GLP-1. Dating back to 1952, PolyPeptide today runs a global network of six GMP-certified facilities in Europe, the U.S. and India. PolyPeptide’s shares (SIX: PPGN) are listed on SIX Swiss Exchange. United by Purpose At PolyPeptide, we take pride in contributing to medicines that make a real difference to people's lives and health. Here, you will become part of work that truly matters, every single day. We are driven by our core values: trust, innovation and excellence. This is reflected in how we collaborate, solve problems, and uphold our responsibility for quality and safety for the patients ultimately affected by our work. We are a company undergoing rapid development. Our growth brings a fast-paced environment, change and new opportunities for both employees and the business. Here, you will grow together with us. If you are looking for a workplace where purpose, community and development go hand in hand, then PolyPeptide is the right place for you. About the Role As SAP Test & Release Manager, you will lead the end-to-end test and release processes for our SAP S/4HANA environment – including integrations with satellite systems and third-party applications. You’ll take ownership of planning, coordination, and execution across test phases and releases within business-critical areas such as Finance, Supply Chain, Manufacturing, and Sales. While the role is strategic in nature, it requires a solid understanding of ERP systems and regulated environments to ensure that changes – whether new features, patches, or upgrades – are delivered in a validated, controlled, and audit-ready manner. You will work closely with stakeholders across compliance, quality, IS/IT, and business functions to ensure testing and release are seamlessly integrated into the ERP implementation and beyond. Key Responsibilities Test Management: * Define and implement SAP testing strategies, plans, and standards. * Coordinate all phases of testing: unit, integration, UAT, regression. * Manage test environments and ensure data integrity during testing. * Oversee defect tracking, test traceability, and documentation. Release Management: * Own and maintain the SAP release calendar in collaboration with stakeholders. * Plan and coordinate deployments, go-lives, and post-release support. * Ensure all releases are timely, low-risk, and fully documented. * Drive stakeholder signoff processes and risk mitigation. Governance & Compliance: * Ensure compliance with internal controls, audits, and change management policies. * Collaborate with Compliance & Validation specialists to maintain system validation. * Contribute to audit readiness and manage release-related documentation. Collaboration & Communication: * Act as the main liaison between technical teams, business users, and external vendors. * Facilitate release readiness reviews and share updates with leadership. * Guide development of documentation standards for testing and release activities. Your Profile You bring both structure and flexibility, with a deep understanding of ERP testing and release in a regulated environment. * A Bachelor’s degree in Computer Science, Information Systems, or similar. * 5+ years of experience in ERP (e.g., SAP, Oracle, Microsoft Dynamics). * Proven experience in test and release management – ideally with SAP S/4HANA. * Familiarity with regulated industries and GxP/CSV requirements is a plus. * Solid knowledge of SDLC, ITIL, and agile methodologies. * Experience with test automation tools and release platforms is a plus. * Proficient in English, both speaking and writing. You thrive in a dynamic, cross-functional setting, and you are motivated by quality, structure, and enabling smooth operations through stable systems. FIND THIS INTERESTING? APPLY NOW! Are you ready to take the next step in your career? The position will be open until August 31 but we are applying an ongoing selection, so do not hesitate to send us your application. Due to summer vacation we will start going through the applications later in August. For more information, please contact Henrik Werdelin at henrik.werdelin@polypeptide.com You are welcome to contact the local union chairman for Akademikerföreningen or Unionen at +46 040-36 62 00 for support.

DDLS INDUSTRIAL PHD POSITION We are announcing a position for a Data-Driven Life Science (DDLS) PhD student in data-driven precision medicine and diagnostics. To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. A doctoral degree corresponds to four years of full-time study. This is an industry PhD project which is a collaboration between the Karolinska Institute, SciLifeLab and Ribocure Pharmaceuticals AB. The PhD student will be employed by Ribocure Pharmaceuticals AB but admitted to PhD studies at the Karolinska Institute. The studies will primarily take place at the Karolinska Institute and SciLifeLab in Stockholm, with frequent research internships at Ribocure Pharmaceuticals AB in Gothenburg. We offer a creative and inspiring environment full of expertise and curiosity. The Karolinska Institute is one of the world's leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At the Karolinska Institute, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Tbe Karolinska Institute collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. Ribocure Pharmaceuticals AB, based in Gothenburg, is a clinical‑stage biotech company developing innovative siRNA‑based therapies. Our research focuses on areas with high unmet medical need, including cardiovascular, metabolic, liver, and kidney diseases. We have access to a strong and vertically integrated platform in oligonucleotide research, spanning from early discovery to clinical development. Our goal is to turn cutting‑edge science into new medicines for patients. The PhD project will be embedded in a close collaboration with Ribocure, providing the candidate with valuable exposure to industrial drug development, insight into how academic discoveries are translated into medicines, and experience of working at the interface between fundamental research and therapeutic innovation. PROJECT DESCRIPTION Project title: "RIBO-LINC: Linking data-driven solutions and RNA innovation for liver and cardiometabolic health". An exciting opportunity is available to join a cutting-edge project at the interface of AI, multi-omics, and RNA therapeutics, aiming to transform precision medicine for cardiometabolic and liver diseases. Current therapeutic strategies largely operate at the gene level, overlooking the functional diversity generated by alternative splicing. This project addresses this critical gap by developing data-driven approaches to identify and prioritize isoform-specific therapeutic targets, enabling a new level of precision in RNA-based treatments. The project will combine large-scale multi-omics integration with advanced machine learning, including artificial neural networks, to predict disease-relevant splice variants across cardiometabolic diseases. By leveraging extensive meta-cohort and perturbation datasets, the work aims to uncover isoform-level regulatory mechanisms and guide the development of next-generation RNA therapeutics with improved specificity and reduced off-target effects. Importantly, computational predictions will be directly linked to experimental evaluation of GalNAc-conjugated RNA therapeutics. This position offers a unique opportunity to work in a highly interdisciplinary environment, contributing to the development of transformative therapies at the forefront of AI-driven biomedical research. QUALIFICATION REQUIREMENTS To be admitted to postgraduate education, the applicant must meet the general and specific entry requirements. The qualification requirements must be met by the deadline for applications. You meet the (A) general entry requirements if you: 1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or 2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or 3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.* Follow the instructions on the web page Entry requirements (eligibility) for doctoral education. *If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education. To meet the (B) specific entry requirements, the applicant must have 1. credits in Life Science, Computer Science Mathematics, Physics or Bioinformatics or alike, including a 30 credit Degree Project (thesis). 2. proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school. Follow the instructions on the web page English language requirements for doctoral education. Verification of your documents: The Karolinska Institute checks the authenticity of your documents and reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action. Additional preferred qualifications: * Prior experience with bioinformatics workflows and analysis of large-scale multi-omics datasets (e.g., RNA-seq, proteomics, long-read sequencing). * Familiarity with machine learning approaches, particularly artificial neural networks, and their application to biological data. * Experience with workflow management systems (e.g., Snakemake, Nextflow) and reproducible data processing pipelines. * Knowledge of transcriptomics and alternative splicing analysis, including isoform-level quantification tools. * Programming skills in R and/or Python, with experience in data integration and statistical analysis. * Exposure to RNA therapeutics or functional genomics approaches is an advantage. * Strong interest in interdisciplinary research combining computational biology with experimental validation. SELECTION The selection among eligible candidates will be based on their ability to successfully complete the PhD studies. Key criteria include analytical thinking, the capacity to work independently and collaboratively, as well as creativity, initiative, and a strong interest in interdisciplinary research. The assessment will be based on: * Technical Expertise: Documented experience in R and/or Python, with proficiency in bioinformatics and analysis of multi-omics datasets (e.g., RNA-seq, proteomics, long-read sequencing). Familiarity with machine learning approaches, particularly neural networks, and experience with workflow management systems (e.g., Snakemake, Nextflow). Knowledge of transcriptomics and alternative splicing analysis. * Academic and Research Excellence: Demonstrated high-quality academic performance, including strong grades and relevant degree projects. Prior research experience in computational biology, functional genomics, or related fields will be highly valued. * Soft Skills and Research Attributes: Excellent written and oral communication skills in English, strong analytical and problem-solving abilities, and the capacity to work both independently and in collaborative, interdisciplinary environments. Creativity, initiative, and a structured approach to complex data analysis are essential. * Motivation and Fit: A well-articulated motivation letter describing the candidate’s interest in AI-driven multi-omics integration and RNA therapeutics. The candidate should demonstrate enthusiasm for bridging computational and experimental research. Final evaluation will include interviews and reference checks to assess overall fit and potential. TERMS AND CONDITIONS The doctoral student will be employed at Ribocure Pharmaceuticals with affiliation to Karolinska Institute on a doctoral studentship maximum 4 years full-time. APPLICATION PROCESS Submit your application and supporting documents through Ribocure Pharmaceuticals AB recruitment system. We prefer that your application is written in English, but you can also apply in Swedish. Deadline to apply is August 2nd 2026. Your application must contain the following documents: * A personal letter and a curriculum vitae * Degree projects and previous publications, if any * Any other documentation showing the desirable skills and personal qualities described above * Documents certifying your general eligibility (see A above) * Documents certifying your specific eligibility (see B above) DDLS AND THE SCILIFELAB SciLifeLab is a national center for molecular biosciences with a focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource hosted by Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University. The center also collaborates with several other universities. Data-driven life science (DDLS) uses data, computational methods and artificial intelligence to study biological systems and processes at all levels, from molecular structures and cellular processes to human health and global ecosystems. The SciLifeLab and Wallenberg National Program for Data-Driven Life Science (DDLS) aims to recruit and train the next generation of data-driven life scientists and to create globally leading computational and data science capabilities in Sweden. The program is funded with a total of 3.3 billion SEK over 12 years from the Knut and Alice Wallenberg (KAW) Foundation. In 2026 the DDLS Research School will be expanded with the recruitment of 25 academic and 7 industrial PhD students. During the course of the DDLS program more than 260 PhD students and 200 postdocs will be part of the Research School. The DDLS program has four strategic research areas: cell and molecular biology, evolution and biodiversity, precision medicine and diagnostics, epidemiology and biology of infection. For more information, please see https://www.scilifelab.se/data-driven/ddls-research-school/ The future of life science is data-driven. Will you be part of that change? Then join us in this unique program! USEFUL LINKS Ribocure Pharmaceuticals AB Claudia Kutter Research group at the Karolinska Institute and SciLifeLab DDLS Research School FOR ANY QUESTIONS REGARDING THE POSITION PLEASE CONTACT: JULIA GRÖNROS, PHD PROJECT DIRECTOR EXTERNAL INNOVATION JULIA.GRONROS@RIBOCURE.COM RIBOCURE PHARMACEUTICALS AB ______________________________________ CLAUDIA KUTTER PRINCIPAL INVESTIGATOR CLAUDIA.KUTTER@KI.SE KAROLINSKA INSTITUTE